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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology; Moebus S, Mecocci P,… See abstract for full author list ➔ Lambert JC, et al. Among authors: lovestone s. Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27. Nat Genet. 2013. PMID: 24162737 Free PMC article.
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
Kehoe PG, Russ C, McIlory S, Williams H, Holmans P, Holmes C, Liolitsa D, Vahidassr D, Powell J, McGleenon B, Liddell M, Plomin R, Dynan K, Williams N, Neal J, Cairns NJ, Wilcock G, Passmore P, Lovestone S, Williams J, Owen MJ. Kehoe PG, et al. Among authors: lovestone s. Nat Genet. 1999 Jan;21(1):71-2. doi: 10.1038/5009. Nat Genet. 1999. PMID: 9916793 No abstract available.
Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.
Morgan AR, Turic D, Jehu L, Hamilton G, Hollingworth P, Moskvina V, Jones L, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Morgan AR, et al. Among authors: lovestone s. Am J Med Genet B Neuropsychiatr Genet. 2007 Sep 5;144B(6):762-70. doi: 10.1002/ajmg.b.30509. Am J Med Genet B Neuropsychiatr Genet. 2007. PMID: 17373700
Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.
Harold D, Jehu L, Turic D, Hollingworth P, Moore P, Summerhayes P, Moskvina V, Foy C, Archer N, Hamilton BA, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Jones L, O'Donovan MC, Owen MJ, Williams J. Harold D, et al. Among authors: lovestone s. Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5;144B(4):448-52. doi: 10.1002/ajmg.b.30456. Am J Med Genet B Neuropsychiatr Genet. 2007. PMID: 17440933
Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.
Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, Hollingworth P, Moskvina V, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan M, Powell J, Lovestone S, Williams J, Owen MJ. Morgan AR, et al. Among authors: lovestone s. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):727-31. doi: 10.1002/ajmg.b.30670. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 18163421
Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Morgan AR, et al. Among authors: lovestone s. Am J Med Genet B Neuropsychiatr Genet. 2009 Jan 5;150B(1):61-4. doi: 10.1002/ajmg.b.30768. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 18452187
Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease.
Kauwe JS, Bertelsen S, Mayo K, Cruchaga C, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Morris JC, Goate AM; Alzheimer's Disease Neuroimaging Initiative. Kauwe JS, et al. Among authors: lovestone s. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):955-9. doi: 10.1002/ajmg.b.31053. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 20029940 Free PMC article.
481 results