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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C. Freed-Pastor WA, et al. Among authors: lowe sw. Cell. 2012 Jan 20;148(1-2):244-58. doi: 10.1016/j.cell.2011.12.017. Cell. 2012. PMID: 22265415 Free PMC article.
E1A signaling to p53 involves the p19(ARF) tumor suppressor.
de Stanchina E, McCurrach ME, Zindy F, Shieh SY, Ferbeyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ, Lowe SW. de Stanchina E, et al. Among authors: lowe sw. Genes Dev. 1998 Aug 1;12(15):2434-42. doi: 10.1101/gad.12.15.2434. Genes Dev. 1998. PMID: 9694807 Free PMC article.
Dissecting p53 tumor suppressor functions in vivo.
Schmitt CA, Fridman JS, Yang M, Baranov E, Hoffman RM, Lowe SW. Schmitt CA, et al. Among authors: lowe sw. Cancer Cell. 2002 Apr;1(3):289-98. doi: 10.1016/s1535-6108(02)00047-8. Cancer Cell. 2002. PMID: 12086865 Free article.
PML is a direct p53 target that modulates p53 effector functions.
de Stanchina E, Querido E, Narita M, Davuluri RV, Pandolfi PP, Ferbeyre G, Lowe SW. de Stanchina E, et al. Among authors: lowe sw. Mol Cell. 2004 Feb 27;13(4):523-35. doi: 10.1016/s1097-2765(04)00062-0. Mol Cell. 2004. PMID: 14992722 Free article.
370 results