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A meta-analysis of genome-wide association studies of epigenetic age acceleration.
Gibson J, Russ TC, Clarke TK, Howard DM, Hillary RF, Evans KL, Walker RM, Bermingham ML, Morris SW, Campbell A, Hayward C, Murray AD, Porteous DJ, Horvath S, Lu AT, McIntosh AM, Whalley HC, Marioni RE. Gibson J, et al. Among authors: lu at. PLoS Genet. 2019 Nov 18;15(11):e1008104. doi: 10.1371/journal.pgen.1008104. eCollection 2019 Nov. PLoS Genet. 2019. PMID: 31738745 Free PMC article.
Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.
Eggert SL, Huyck KL, Somasundaram P, Kavalla R, Stewart EA, Lu AT, Painter JN, Montgomery GW, Medland SE, Nyholt DR, Treloar SA, Zondervan KT, Heath AC, Madden PA, Rose L, Buring JE, Ridker PM, Chasman DI, Martin NG, Cantor RM, Morton CC. Eggert SL, et al. Among authors: lu at. Am J Hum Genet. 2012 Oct 5;91(4):621-8. doi: 10.1016/j.ajhg.2012.08.009. Am J Hum Genet. 2012. PMID: 23040493 Free PMC article.
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
Luykx JJ, Bakker SC, Lentjes E, Neeleman M, Strengman E, Mentink L, DeYoung J, de Jong S, Sul JH, Eskin E, van Eijk K, van Setten J, Buizer-Voskamp JE, Cantor RM, Lu A, van Amerongen M, van Dongen EP, Keijzers P, Kappen T, Borgdorff P, Bruins P, Derks EM, Kahn RS, Ophoff RA. Luykx JJ, et al. Mol Psychiatry. 2014 Feb;19(2):228-34. doi: 10.1038/mp.2012.183. Epub 2013 Jan 15. Mol Psychiatry. 2014. PMID: 23319000
The cerebellum ages slowly according to the epigenetic clock.
Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, Vinters HV, Coles LS. Horvath S, et al. Among authors: lu at. Aging (Albany NY). 2015 May;7(5):294-306. doi: 10.18632/aging.100742. Aging (Albany NY). 2015. PMID: 26000617 Free PMC article.
Menopause accelerates biological aging.
Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Bandinelli S, Salfati E, Manson JE, Quach A, Kusters CD, Kuh D, Wong A, Teschendorff AE, Widschwendter M, Ritz BR, Absher D, Assimes TL, Horvath S. Levine ME, et al. Among authors: lu at. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9327-32. doi: 10.1073/pnas.1604558113. Epub 2016 Jul 25. Proc Natl Acad Sci U S A. 2016. PMID: 27457926 Free PMC article.
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.
Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL. Horvath S, et al. Among authors: lu at. Genome Biol. 2016 Aug 11;17(1):171. doi: 10.1186/s13059-016-1030-0. Genome Biol. 2016. PMID: 27511193 Free PMC article.
DNA methylation-based measures of biological age: meta-analysis predicting time to death.
Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S. Chen BH, et al. Among authors: lu at. Aging (Albany NY). 2016 Sep 28;8(9):1844-1865. doi: 10.18632/aging.101020. Aging (Albany NY). 2016. PMID: 27690265 Free PMC article.
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors.
Quach A, Levine ME, Tanaka T, Lu AT, Chen BH, Ferrucci L, Ritz B, Bandinelli S, Neuhouser ML, Beasley JM, Snetselaar L, Wallace RB, Tsao PS, Absher D, Assimes TL, Stewart JD, Li Y, Hou L, Baccarelli AA, Whitsel EA, Horvath S. Quach A, et al. Among authors: lu at. Aging (Albany NY). 2017 Feb 14;9(2):419-446. doi: 10.18632/aging.101168. Aging (Albany NY). 2017. PMID: 28198702 Free PMC article.
122 results