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MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.
Surakka I, Fritsche LG, Zhou W, Backman J, Kosmicki JA, Lu H, Brumpton B, Nielsen JB, Gabrielsen ME, Skogholt AH, Wolford B, Graham SE, Chen YE, Lee S, Kang HM, Langhammer A, Forsmo S, Åsvold BO, Styrkarsdottir U, Holm H, Gudbjartsson D, Stefansson K, Baras A; Regeneron Genetics Center; Abecasis GR, Hveem K, Willer CJ. Surakka I, et al. Among authors: lu h. Nat Commun. 2020 Oct 23;11(1):4093. doi: 10.1038/s41467-020-17315-0. Nat Commun. 2020. PMID: 33097703 Free PMC article.
Krüppel-like factors and vascular wall homeostasis.
Fan Y, Lu H, Liang W, Hu W, Zhang J, Chen YE. Fan Y, et al. Among authors: lu h. J Mol Cell Biol. 2017 Oct 1;9(5):352-363. doi: 10.1093/jmcb/mjx037. J Mol Cell Biol. 2017. PMID: 28992202 Free PMC article. Review.
Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.
Roychowdhury T, Lu H, Hornsby WE, Crone B, Wang GT, Guo DC, Sendamarai AK, Devineni P, Lin M, Zhou W, Graham SE, Wolford BN, Surakka I, Wang Z, Chang L, Zhang J, Mathis M, Brummett CM, Melendez TL, Shea MJ, Kim KM, Deeb GM, Patel HJ, Eliason J, Eagle KA, Yang B, Ganesh SK, Brumpton B, Åsvold BO, Skogholt AH, Hveem K; VA Million Veteran Program; Pyarajan S, Klarin D, Tsao PS, Damrauer SM, Leal SM, Milewicz DM, Chen YE, Garcia-Barrio MT, Willer CJ. Roychowdhury T, et al. Among authors: lu h. Am J Hum Genet. 2021 Sep 2;108(9):1578-1589. doi: 10.1016/j.ajhg.2021.06.016. Epub 2021 Jul 14. Am J Hum Genet. 2021. PMID: 34265237 Free PMC article.
Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2.
Fan Y, Wolford BN, Lu H, Liang W, Sun J, Zhou W, Rom O, Mahajan A, Surakka I, Graham SE, Liu Z, Kim H, Ramdas S, Fritsche LG, Nielsen JB, Gabrielsen ME, Hveem K, Yang D, Song J, Garcia-Barrio MT, Zhang J, Liu W, Zhang K, Willer CJ, Chen YE. Fan Y, et al. Among authors: lu h. iScience. 2021 Oct 2;24(11):103196. doi: 10.1016/j.isci.2021.103196. eCollection 2021 Nov 19. iScience. 2021. PMID: 34746691 Free PMC article.
Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis.
Zhu W, Liang W, Lu H, Chang L, Zhang J, Chen YE, Guo Y. Zhu W, et al. Among authors: lu h. Cells. 2022 Sep 15;11(18):2877. doi: 10.3390/cells11182877. Cells. 2022. PMID: 36139452 Free PMC article.
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