Lukas TJ - Search Results

1

Effect of fluoxetine on disease progression in a mouse model of ALS.

Koschnitzky JE, Quinlan KA, Lukas TJ, Kajtaz E, Kocevar EJ, Mayers WF, Siddique T, Heckman CJ. Koschnitzky JE, et al. Among authors: lukas tj. J Neurophysiol. 2014 Jun 1;111(11):2164-76. doi: 10.1152/jn.00425.2013. Epub 2014 Mar 5. J Neurophysiol. 2014. PMID: 24598527 Free PMC article.

2

Informatics-assisted protein profiling in a transgenic mouse model of amyotrophic lateral sclerosis.

Lukas TJ, Luo WW, Mao H, Cole N, Siddique T. Lukas TJ, et al. Mol Cell Proteomics. 2006 Jul;5(7):1233-44. doi: 10.1074/mcp.M500431-MCP200. Epub 2006 Mar 29. Mol Cell Proteomics. 2006. PMID: 16571896 Free article.

3

ACTH (Acthar Gel) Reduces Toxic SOD1 Protein Linked to Amyotrophic Lateral Sclerosis in Transgenic Mice: A Novel Observation.

Arrat H, Lukas TJ, Siddique T. Arrat H, et al. Among authors: lukas tj. PLoS One. 2015 May 8;10(5):e0125638. doi: 10.1371/journal.pone.0125638. eCollection 2015. PLoS One. 2015. PMID: 25955410 Free PMC article.

4

Gender difference in levels of Cu/Zn superoxide dismutase (SOD1) in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

Frutiger K, Lukas TJ, Gorrie G, Ajroud-Driss S, Siddique T. Frutiger K, et al. Among authors: lukas tj. Amyotroph Lateral Scler. 2008 Jun;9(3):184-7. doi: 10.1080/17482960801984358. Amyotroph Lateral Scler. 2008. PMID: 18574763

5

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.

Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH, Lukas T, Dal Canto MC, O'Halloran TV, Siddique T. Deng HX, et al. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7142-7. doi: 10.1073/pnas.0602046103. Epub 2006 Apr 24. Proc Natl Acad Sci U S A. 2006. PMID: 16636275 Free PMC article.

6

Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.

Ajroud-Driss S, Saeed M, Khan H, Siddique N, Hung WY, Sufit R, Heller S, Armstrong J, Casey P, Siddique T, Lukas TJ. Ajroud-Driss S, et al. Among authors: lukas tj. Amyotroph Lateral Scler. 2007 Oct;8(5):305-9. doi: 10.1080/17482960701500650. Amyotroph Lateral Scler. 2007. PMID: 17852022 Clinical Trial.

7

Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression.

Lukas TJ, Schiltz GE, Arrat H, Scheidt K, Siddique T. Lukas TJ, et al. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1532-7. doi: 10.1016/j.bmcl.2014.01.078. Epub 2014 Feb 8. Bioorg Med Chem Lett. 2014. PMID: 24560539 Free article.

8

Compound heterozygote mutations in SPG7 in a family with adult-onset primary lateral sclerosis.

Yang Y, Zhang L, Lynch DR, Lukas T, Ahmeti K, Sleiman PM, Ryan E, Schadt KA, Newman JH, Deng HX, Siddique N, Siddique T. Yang Y, et al. Neurol Genet. 2016 Mar 3;2(2):e60. doi: 10.1212/NXG.0000000000000060. eCollection 2016 Apr. Neurol Genet. 2016. PMID: 27123479 Free PMC article.

9

Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge.

Lukas TJ, Mirzoeva S, Slomczynska U, Watterson DM. Lukas TJ, et al. J Med Chem. 1999 Mar 11;42(5):910-9. doi: 10.1021/jm980573a. J Med Chem. 1999. PMID: 10072688

10

Transglutaminase-catalyzed crosslinking of the Aalpha and gamma constituent chains in fibrinogen.

Murthy SN, Wilson JH, Lukas TJ, Veklich Y, Weisel JW, Lorand L. Murthy SN, et al. Among authors: lukas tj. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):44-8. doi: 10.1073/pnas.97.1.44. Proc Natl Acad Sci U S A. 2000. PMID: 10618368 Free PMC article.

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