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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.
Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P; Anorexia Nervosa Genetics Initiative; Hanscombe KB, Purves KL; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, K… See abstract for full author list ➔ Watson HJ, et al. Among authors: luykx j. Nat Genet. 2019 Aug;51(8):1207-1214. doi: 10.1038/s41588-019-0439-2. Epub 2019 Jul 15. Nat Genet. 2019. PMID: 31308545 Free PMC article.
The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism.
Vinkers CH, Van Gastel WA, Schubart CD, Van Eijk KR, Luykx JJ, Van Winkel R, Joëls M, Ophoff RA, Boks MP; Genetic Risk and OUtcome of Psychosis (GROUP) Investigators; Bruggeman R, Cahn W, de Haan L, Kahn RS, Meijer CJ, Myin-Germeys I, van Os J, Wiersma D. Vinkers CH, et al. Among authors: luykx jj. Schizophr Res. 2013 Oct;150(1):303-11. doi: 10.1016/j.schres.2013.07.020. Epub 2013 Aug 15. Schizophr Res. 2013. PMID: 23954148 Free article.
Seasonal changes in gene expression represent cell-type composition in whole blood.
De Jong S, Neeleman M, Luykx JJ, ten Berg MJ, Strengman E, Den Breeijen HH, Stijvers LC, Buizer-Voskamp JE, Bakker SC, Kahn RS, Horvath S, Van Solinge WW, Ophoff RA. De Jong S, et al. Among authors: luykx jj. Hum Mol Genet. 2014 May 15;23(10):2721-8. doi: 10.1093/hmg/ddt665. Epub 2014 Jan 7. Hum Mol Genet. 2014. PMID: 24399446 Free PMC article.
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.
Luykx JJ, Bakker SC, Visser WF, Verhoeven-Duif N, Buizer-Voskamp JE, den Heijer JM, Boks MP, Sul JH, Eskin E, Ori AP, Cantor RM, Vorstman J, Strengman E, DeYoung J, Kappen TH, Pariama E, van Dongen EP, Borgdorff P, Bruins P, de Koning TJ, Kahn RS, Ophoff RA. Luykx JJ, et al. Mol Psychiatry. 2015 Dec;20(12):1557-64. doi: 10.1038/mp.2014.190. Epub 2015 Feb 10. Mol Psychiatry. 2015. PMID: 25666758
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium. McLaughlin RL, et al. Among authors: luykx jj. Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774. Nat Commun. 2017. PMID: 28322246 Free PMC article.
Mendelian Randomization Concerns.
Lin BD, Li Y, Luykx J. Lin BD, et al. Among authors: luykx j. JAMA Psychiatry. 2018 Apr 1;75(4):407. doi: 10.1001/jamapsychiatry.2018.0035. JAMA Psychiatry. 2018. PMID: 29516079 No abstract available.
The role of genetic variation of human metabolism for BMI, mental traits and mental disorders.
Hebebrand J, Peters T, Schijven D, Hebebrand M, Grasemann C, Winkler TW, Heid IM, Antel J, Föcker M, Tegeler L, Brauner L, Adan RAH, Luykx JJ, Correll CU, König IR, Hinney A, Libuda L. Hebebrand J, et al. Among authors: luykx jj. Mol Metab. 2018 Jun;12:1-11. doi: 10.1016/j.molmet.2018.03.015. Epub 2018 Apr 3. Mol Metab. 2018. PMID: 29673576 Free PMC article.
190 results