Lydeard JR - Search Results

1

Break-induced replication and telomerase-independent telomere maintenance require Pol32.

Lydeard JR, Jain S, Yamaguchi M, Haber JE. Lydeard JR, et al. Nature. 2007 Aug 16;448(7155):820-3. doi: 10.1038/nature06047. Epub 2007 Aug 1. Nature. 2007. PMID: 17671506

2

A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair.

Jain S, Sugawara N, Lydeard J, Vaze M, Tanguy Le Gac N, Haber JE. Jain S, et al. Genes Dev. 2009 Feb 1;23(3):291-303. doi: 10.1101/gad.1751209. Genes Dev. 2009. PMID: 19204116 Free PMC article.

3

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.

Lydeard JR, Lipkin-Moore Z, Sheu YJ, Stillman B, Burgers PM, Haber JE. Lydeard JR, et al. Genes Dev. 2010 Jun 1;24(11):1133-44. doi: 10.1101/gad.1922610. Genes Dev. 2010. PMID: 20516198 Free PMC article.

4

Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.

Lydeard JR, Lipkin-Moore Z, Jain S, Eapen VV, Haber JE. Lydeard JR, et al. PLoS Genet. 2010 May 27;6(5):e1000973. doi: 10.1371/journal.pgen.1000973. PLoS Genet. 2010. PMID: 20523895 Free PMC article.

5

Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.

Fischer ES, Böhm K, Lydeard JR, Yang H, Stadler MB, Cavadini S, Nagel J, Serluca F, Acker V, Lingaraju GM, Tichkule RB, Schebesta M, Forrester WC, Schirle M, Hassiepen U, Ottl J, Hild M, Beckwith RE, Harper JW, Jenkins JL, Thomä NH. Fischer ES, et al. Among authors: lydeard jr. Nature. 2014 Aug 7;512(7512):49-53. doi: 10.1038/nature13527. Epub 2014 Jul 16. Nature. 2014. PMID: 25043012 Free PMC article.

6

Inhibitors for E3 ubiquitin ligases.

Lydeard JR, Harper JW. Lydeard JR, et al. Nat Biotechnol. 2010 Jul;28(7):682-4. doi: 10.1038/nbt0710-682. Nat Biotechnol. 2010. PMID: 20622837 No abstract available.

7

Building and remodelling Cullin-RING E3 ubiquitin ligases.

Lydeard JR, Schulman BA, Harper JW. Lydeard JR, et al. EMBO Rep. 2013 Dec;14(12):1050-61. doi: 10.1038/embor.2013.173. Epub 2013 Nov 15. EMBO Rep. 2013. PMID: 24232186 Free PMC article. Review.

8

Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8.

Scott DC, Sviderskiy VO, Monda JK, Lydeard JR, Cho SE, Harper JW, Schulman BA. Scott DC, et al. Among authors: lydeard jr. Cell. 2014 Jun 19;157(7):1671-84. doi: 10.1016/j.cell.2014.04.037. Cell. 2014. PMID: 24949976 Free PMC article.

9

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Raman M, et al. Among authors: lydeard jr. Nat Cell Biol. 2015 Oct;17(10):1356-69. doi: 10.1038/ncb3238. Epub 2015 Sep 21. Nat Cell Biol. 2015. PMID: 26389662 Free PMC article.

10

Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.

Monda JK, Scott DC, Miller DJ, Lydeard J, King D, Harper JW, Bennett EJ, Schulman BA. Monda JK, et al. Structure. 2013 Jan 8;21(1):42-53. doi: 10.1016/j.str.2012.10.013. Epub 2012 Nov 29. Structure. 2013. PMID: 23201271 Free PMC article.

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