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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, Xiang J, Zhang T, Theilen TM, García-Santos G, Williams C, Ararso Y, Huang Y, Rodrigues G, Shen TL, Labori KJ, Lothe IM, Kure EH, Hernandez J, Doussot A, Ebbesen SH, Grandgenett PM, Hollingsworth MA, Jain M, Mallya K, Batra SK, Jarnagin WR, Schwartz RE, Matei I, Peinado H, Stanger BZ, Bromberg J, Lyden D. Costa-Silva B, et al. Among authors: lyden d. Nat Cell Biol. 2015 Jun;17(6):816-26. doi: 10.1038/ncb3169. Epub 2015 May 18. Nat Cell Biol. 2015. PMID: 25985394 Free PMC article.
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.
Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, Shido K, Jin DK, Dias S, Zhang F, Hartman TE, Hackett NR, Crystal RG, Witte L, Hicklin DJ, Bohlen P, Eaton D, Lyden D, de Sauvage F, Rafii S. Avecilla ST, et al. Among authors: lyden d. Nat Med. 2004 Jan;10(1):64-71. doi: 10.1038/nm973. Epub 2003 Dec 21. Nat Med. 2004. PMID: 14702636
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. Kaplan RN, et al. Among authors: lyden d. Nature. 2005 Dec 8;438(7069):820-7. doi: 10.1038/nature04186. Nature. 2005. PMID: 16341007 Free PMC article.
Preparing the "soil": the premetastatic niche.
Kaplan RN, Rafii S, Lyden D. Kaplan RN, et al. Among authors: lyden d. Cancer Res. 2006 Dec 1;66(23):11089-93. doi: 10.1158/0008-5472.CAN-06-2407. Cancer Res. 2006. PMID: 17145848 Free PMC article. Review.
Niche-to-niche migration of bone-marrow-derived cells.
Kaplan RN, Psaila B, Lyden D. Kaplan RN, et al. Among authors: lyden d. Trends Mol Med. 2007 Feb;13(2):72-81. doi: 10.1016/j.molmed.2006.12.003. Epub 2007 Jan 2. Trends Mol Med. 2007. PMID: 17197241 Review.
Inflammation joins the "niche".
Peinado H, Rafii S, Lyden D. Peinado H, et al. Among authors: lyden d. Cancer Cell. 2008 Nov 4;14(5):347-9. doi: 10.1016/j.ccr.2008.10.012. Cancer Cell. 2008. PMID: 18977322 Free PMC article.
The metastatic niche: adapting the foreign soil.
Psaila B, Lyden D. Psaila B, et al. Among authors: lyden d. Nat Rev Cancer. 2009 Apr;9(4):285-93. doi: 10.1038/nrc2621. Nat Rev Cancer. 2009. PMID: 19308068 Free PMC article. Review.
146 results