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Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
Seppälä I, Kleber ME, Lyytikäinen LP, Hernesniemi JA, Mäkelä KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kähönen N, Alfthan G, Viikari JS, Kähonen M, Raitakari OT, März W, Meinitzer A, Lehtimäki T; AtheroRemo Consortium. Seppälä I, et al. Among authors: makela km. Eur Heart J. 2014 Feb;35(8):524-31. doi: 10.1093/eurheartj/eht447. Epub 2013 Oct 24. Eur Heart J. 2014. PMID: 24159190 Free article.
Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.
Mäkelä KM, Seppälä I, Hernesniemi JA, Lyytikäinen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kähönen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjärvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JS, Kähönen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, März W, Lehtimäki T. Mäkelä KM, et al. Circ Cardiovasc Genet. 2013 Feb;6(1):73-81. doi: 10.1161/CIRCGENETICS.112.964965. Epub 2012 Dec 17. Circ Cardiovasc Genet. 2013. PMID: 23247145
Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.
Kleber ME, Seppälä I, Pilz S, Hoffmann MM, Tomaschitz A, Oksala N, Raitoharju E, Lyytikäinen LP, Mäkelä KM, Laaksonen R, Kähönen M, Raitakari OT, Huang J, Kienreich K, Fahrleitner-Pammer A, Drechsler C, Krane V, Boehm BO, Koenig W, Wanner C, Lehtimäki T, März W, Meinitzer A. Kleber ME, et al. Among authors: makela km. Circ Cardiovasc Genet. 2013 Oct;6(5):505-13. doi: 10.1161/CIRCGENETICS.113.000108. Epub 2013 Sep 18. Circ Cardiovasc Genet. 2013. PMID: 24047826
Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events.
Mäkelä KM, Traylor M, Oksala N, Kleber ME, Seppälä I, Lyytikäinen LP, Hernesniemi JA, Kähönen M, Bevan S, Rothwell PM, Sudlow C, Dichgans M; Wellcome Trust Case Control Consortium 2 (WTCCC2); Delgado G, Grammer TB, Scharnagl H, Markus HS, März W, Lehtimäki T. Mäkelä KM, et al. Atherosclerosis. 2014 May;234(1):214-7. doi: 10.1016/j.atherosclerosis.2014.03.002. Epub 2014 Mar 14. Atherosclerosis. 2014. PMID: 24681816
Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke.
Seppälä I, Kleber ME, Bevan S, Lyytikäinen LP, Oksala N, Hernesniemi JA, Mäkelä KM, Rothwell PM, Sudlow C, Dichgans M, Mononen N, Vlachopoulou E, Sinisalo J, Delgado GE, Laaksonen R, Koskinen T, Scharnagl H, Kähönen M, Markus HS, März W, Lehtimäki T. Seppälä I, et al. Among authors: makela km. Sci Rep. 2016 Mar 17;6:23207. doi: 10.1038/srep23207. Sci Rep. 2016. PMID: 26984639 Free PMC article.
Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).
Oksala N, Pärssinen J, Seppälä I, Raitoharju E, Kholova I, Hernesniemi J, Lyytikäinen LP, Levula M, Mäkelä KM, Sioris T, Kähönen M, Laaksonen R, Hytönen V, Lehtimäki T. Oksala N, et al. Among authors: makela km. Circ Cardiovasc Genet. 2013 Dec;6(6):579-87. doi: 10.1161/CIRCGENETICS.113.000141. Epub 2013 Oct 11. Circ Cardiovasc Genet. 2013. PMID: 24122613
Vascular cell adhesion molecule 1, soluble Fas and hepatocyte growth factor as predictors of mortality in nonagenarians: the Vitality 90+ study.
Kämppä N, Mäkelä KM, Lyytikäinen LP, Peltonen N, Hautamäki J, Seppälä I, Mononen N, Goebeler S, Karhunen PJ, Hervonen A, Hurme M, Jylhä M, Lehtimäki T. Kämppä N, et al. Among authors: makela km. Exp Gerontol. 2013 Nov;48(11):1167-72. doi: 10.1016/j.exger.2013.07.009. Epub 2013 Jul 30. Exp Gerontol. 2013. PMID: 23911532
A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.
Traylor M, Mäkelä KM, Kilarski LL, Holliday EG, Devan WJ, Nalls MA, Wiggins KL, Zhao W, Cheng YC, Achterberg S, Malik R, Sudlow C, Bevan S, Raitoharju E; METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2); Oksala N, Thijs V, Lemmens R, Lindgren A, Slowik A, Maguire JM, Walters M, Algra A, Sharma P, Attia JR, Boncoraglio GB, Rothwell PM, de Bakker PI, Bis JC, Saleheen D, Kittner SJ, Mitchell BD, Rosand J, Meschia JF, Levi C, Dichgans M, Lehtimäki T, Lewis CM, Markus HS. Traylor M, et al. Among authors: makela km. PLoS Genet. 2014 Jul 31;10(7):e1004469. doi: 10.1371/journal.pgen.1004469. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25078452 Free PMC article.
Afamin predicts the prevalence and incidence of nonalcoholic fatty liver disease.
Pitkänen N, Finkenstedt A, Lamina C, Juonala M, Kähönen M, Mäkelä KM, Dieplinger B, Viveiros A, Melmer A, Leitner I, Kedenko L, Seppälä I, Viikari JSA, Mueller T, Kronenberg F, Paulweber B, Lehtimäki T, Zoller H, Raitakari OT, Dieplinger H. Pitkänen N, et al. Among authors: makela km. Clin Chem Lab Med. 2021 Dec 2;60(2):243-251. doi: 10.1515/cclm-2021-0837. Print 2022 Jan 27. Clin Chem Lab Med. 2021. PMID: 34850615 Free article.
25 results