MC_U105178806/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

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Year	Number of Results
2005	1
2006	5
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2008	5
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2010	3
2011	8
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The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.

Safavi S, Larouche A, Zahn A, Patenaude AM, Domanska D, Dionne K, Rognes T, Dingler F, Kang SK, Liu Y, Johnson N, Hébert J, Verdun RE, Rada CA, Vega F, Nilsen H, Di Noia JM. Safavi S, et al. NAR Cancer. 2020 Aug 27;2(3):zcaa019. doi: 10.1093/narcan/zcaa019. eCollection 2020 Sep. NAR Cancer. 2020. PMID: 33554121 Free PMC article.

Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex.

Shapson-Coe A, Valeiras B, Wall C, Rada C. Shapson-Coe A, et al. PLoS One. 2019 Mar 19;14(3):e0213553. doi: 10.1371/journal.pone.0213553. eCollection 2019. PLoS One. 2019. PMID: 30889214 Free PMC article.

Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle.

Sato Y, Ohtsubo H, Nihei N, Kaneko T, Sato Y, Adachi SI, Kondo S, Nakamura M, Mizunoya W, Iida H, Tatsumi R, Rada C, Yoshizawa F. Sato Y, et al. FASEB J. 2018 Mar;32(3):1428-1439. doi: 10.1096/fj.201700493R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29127187 Free PMC article.

Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.

Alsøe L, Sarno A, Carracedo S, Domanska D, Dingler F, Lirussi L, SenGupta T, Tekin NB, Jobert L, Alexandrov LB, Galashevskaya A, Rada C, Sandve GK, Rognes T, Krokan HE, Nilsen H. Alsøe L, et al. Sci Rep. 2017 Aug 3;7(1):7199. doi: 10.1038/s41598-017-07314-5. Sci Rep. 2017. PMID: 28775312 Free PMC article.

Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE.

Wu YL, Stubbington MJ, Daly M, Teichmann SA, Rada C. Wu YL, et al. J Exp Med. 2017 Jan;214(1):183-196. doi: 10.1084/jem.20161056. Epub 2016 Dec 19. J Exp Med. 2017. PMID: 27994069 Free PMC article.

Directed evolution of human scFvs in DT40 cells.

Lim AW, Williams GT, Rada C, Sale JE. Lim AW, et al. Protein Eng Des Sel. 2016 Feb;29(2):39-48. doi: 10.1093/protein/gzv058. Epub 2015 Oct 30. Protein Eng Des Sel. 2016. PMID: 26519451 Free PMC article.

Mutagenesis by AID: Being in the Right Place at the Right Time.

Rada C. Rada C. PLoS Genet. 2015 Sep 10;11(9):e1005489. doi: 10.1371/journal.pgen.1005489. eCollection 2015 Sep. PLoS Genet. 2015. PMID: 26355597 Free PMC article. No abstract available.

CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.

van Maldegem F, Maslen S, Johnson CM, Chandra A, Ganesh K, Skehel M, Rada C. van Maldegem F, et al. Nucleic Acids Res. 2015 Aug 18;43(14):7058-69. doi: 10.1093/nar/gkv643. Epub 2015 Jun 29. Nucleic Acids Res. 2015. PMID: 26130721 Free PMC article.

Pillars article: AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature. 2002. 418: 99-103.

Petersen-Mahrt SK, Harris RS, Neuberger MS. Petersen-Mahrt SK, et al. J Immunol. 2015 Mar 1;194(5):2043-7. J Immunol. 2015. PMID: 25710957 No abstract available.

Active RNAP pre-initiation sites are highly mutated by cytidine deaminases in yeast, with AID targeting small RNA genes.

Taylor BJ, Wu YL, Rada C. Taylor BJ, et al. Elife. 2014 Sep 19;3:e03553. doi: 10.7554/eLife.03553. Elife. 2014. PMID: 25237741 Free PMC article.

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