MC_U120085811/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2009	1
2011	1
2012	1
2013	6
2014	6
2015	3
2016	1
2017	3
2018	1
2019	1
2020	1
2024	0

1

Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.

Roman-Trufero M, Ito CM, Pedebos C, Magdalou I, Wang YF, Karimi MM, Moyon B, Webster Z, di Gregorio A, Azuara V, Khalid S, Speck C, Rodriguez T, Dillon N. Roman-Trufero M, et al. Mol Biol Evol. 2020 Jul 1;37(7):1986-2001. doi: 10.1093/molbev/msaa060. Mol Biol Evol. 2020. PMID: 32145025 Free PMC article.

2

An integrated workflow for crosslinking mass spectrometry.

Mendes ML, Fischer L, Chen ZA, Barbon M, O'Reilly FJ, Giese SH, Bohlke-Schneider M, Belsom A, Dau T, Combe CW, Graham M, Eisele MR, Baumeister W, Speck C, Rappsilber J. Mendes ML, et al. Mol Syst Biol. 2019 Sep;15(9):e8994. doi: 10.15252/msb.20198994. Mol Syst Biol. 2019. PMID: 31556486 Free PMC article.

3

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MR, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, Treitschke S, Dörken B, Speck C, Mallette FA, Zon LI, Holmen SL, Peeper DS, Samuels Y, Schmitt CA, Lee S. Yu Y, et al. Cancer Cell. 2018 Feb 12;33(2):322-336.e8. doi: 10.1016/j.ccell.2018.01.002. Cancer Cell. 2018. PMID: 29438700 Free PMC article.

4

Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.

Noguchi Y, Yuan Z, Bai L, Schneider S, Zhao G, Stillman B, Speck C, Li H. Noguchi Y, et al. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9529-E9538. doi: 10.1073/pnas.1712537114. Epub 2017 Oct 25. Proc Natl Acad Sci U S A. 2017. PMID: 29078375 Free PMC article.

5

From structure to mechanism-understanding initiation of DNA replication.

Riera A, Barbon M, Noguchi Y, Reuter LM, Schneider S, Speck C. Riera A, et al. Genes Dev. 2017 Jun 1;31(11):1073-1088. doi: 10.1101/gad.298232.117. Genes Dev. 2017. PMID: 28717046 Free PMC article. Review.

6

Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.

Yuan Z, Riera A, Bai L, Sun J, Nandi S, Spanos C, Chen ZA, Barbon M, Rappsilber J, Stillman B, Speck C, Li H. Yuan Z, et al. Nat Struct Mol Biol. 2017 Mar;24(3):316-324. doi: 10.1038/nsmb.3372. Epub 2017 Feb 13. Nat Struct Mol Biol. 2017. PMID: 28191893 Free PMC article.

7

Replicating repetitive DNA.

Tognetti S, Speck C. Tognetti S, et al. Nat Cell Biol. 2016 May 27;18(6):593-4. doi: 10.1038/ncb3367. Nat Cell Biol. 2016. PMID: 27230530 Free article.

8

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.

Herrera MC, Tognetti S, Riera A, Zech J, Clarke P, Fernández-Cid A, Speck C. Herrera MC, et al. Nucleic Acids Res. 2015 Dec 2;43(21):10238-50. doi: 10.1093/nar/gkv881. Epub 2015 Sep 3. Nucleic Acids Res. 2015. PMID: 26338774 Free PMC article.

9

Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.

Chang F, Riera A, Evrin C, Sun J, Li H, Speck C, Weinreich M. Chang F, et al. Elife. 2015 Aug 25;4:e05795. doi: 10.7554/eLife.05795. Elife. 2015. PMID: 26305410 Free PMC article.

10

The fidelity of synaptonemal complex assembly is regulated by a signaling mechanism that controls early meiotic progression.

Silva N, Ferrandiz N, Barroso C, Tognetti S, Lightfoot J, Telecan O, Encheva V, Faull P, Hanni S, Furger A, Snijders AP, Speck C, Martinez-Perez E. Silva N, et al. Dev Cell. 2014 Nov 24;31(4):503-11. doi: 10.1016/j.devcel.2014.10.001. Epub 2014 Nov 6. Dev Cell. 2014. PMID: 25455309 Free article.

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