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Page 1
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.
Jones E, Hummerich H, Viré E, Uphill J, Dimitriadis A, Speedy H, Campbell T, Norsworthy P, Quinn L, Whitfield J, Linehan J, Jaunmuktane Z, Brandner S, Jat P, Nihat A, How Mok T, Ahmed P, Collins S, Stehmann C, Sarros S, Kovacs GG, Geschwind MD, Golubjatnikov A, Frontzek K, Budka H, Aguzzi A, Karamujić-Čomić H, van der Lee SJ, Ibrahim-Verbaas CA, van Duijn CM, Sikorska B, Golanska E, Liberski PP, Calero M, Calero O, Sanchez-Juan P, Salas A, Martinón-Torres F, Bouaziz-Amar E, Haïk S, Laplanche JL, Brandel JP, Amouyel P, Lambert JC, Parchi P, Bartoletti-Stella A, Capellari S, Poleggi A, Ladogana A, Pocchiari M, Aneli S, Matullo G, Knight R, Zafar S, Zerr I, Booth S, Coulthart MB, Jansen GH, Glisic K, Blevins J, Gambetti P, Safar J, Appleby B, Collinge J, Mead S. Jones E, et al. Lancet Neurol. 2020 Oct;19(10):840-848. doi: 10.1016/S1474-4422(20)30273-8. Epub 2020 Sep 16. Lancet Neurol. 2020. PMID: 32949544 Free PMC article.
Highly infectious prions are not directly neurotoxic.
Benilova I, Reilly M, Terry C, Wenborn A, Schmidt C, Marinho AT, Risse E, Al-Doujaily H, Wiggins De Oliveira M, Sandberg MK, Wadsworth JDF, Jat PS, Collinge J. Benilova I, et al. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23815-23822. doi: 10.1073/pnas.2007406117. Epub 2020 Sep 8. Proc Natl Acad Sci U S A. 2020. PMID: 32900920 Free PMC article.
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils.
Cerofolini L , Ravera E , Bologna S , Wiglenda T , Böddrich A , Purfürst B , Benilova I , Korsak M , Gallo G , Rizzo D , Gonnelli L , Fragai M , De Strooper B , Wanker EE , Luchinat C . Cerofolini L , et al. Chem Commun (Camb). 2020 Aug 11;56(62):8830-8833. doi: 10.1039/d0cc02463e. Epub 2020 Jul 6. Chem Commun (Camb). 2020. PMID: 32749391
Genetic risk factors for Creutzfeldt-Jakob disease.
Jones E, Mead S. Jones E, et al. Neurobiol Dis. 2020 Aug;142:104973. doi: 10.1016/j.nbd.2020.104973. Epub 2020 Jun 18. Neurobiol Dis. 2020. PMID: 32565065 Free article. Review.