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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR, Caballero A, Geschwind DH, Huckins LM, Ruderfer DM, Santiago E, Sklar P, Stahl EA, Won H, Agerbo E, Als TD, Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J, Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J, Hougaard DM, Mattheisen M, Molden E, Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E, Silagadze T, Hansen CS, Stefansson K, Stefansson H, Steinberg S, Tosato S, Werge T; GERAD1 Consortium; CRESTAR Consortium; Collier DA, Rujescu D, Kirov G, Owen MJ, O'Donovan MC, Walters JTR. Pardiñas AF, et al. Among authors: maccabe jh. Nat Genet. 2018 Mar;50(3):381-389. doi: 10.1038/s41588-018-0059-2. Epub 2018 Feb 26. Nat Genet. 2018. PMID: 29483656 Free PMC article.
Epigenetics, genomic mutations and cognitive function.
Reichenberg A, Mill J, MacCabe JH. Reichenberg A, et al. Among authors: maccabe jh. Cogn Neuropsychiatry. 2009;14(4-5):377-90. doi: 10.1080/13546800902978417. Cogn Neuropsychiatry. 2009. PMID: 19634036 Review.
Opening Pandora's box in the UK: a hypothetical pharmacogenetic test for clozapine.
Spencer BW, Prainsack B, Rujescu D, Giegling I, Collier DA, Gaughran F, MacCabe JH, Barr CL, Sigurdsson E, Stovring H, Malhotra AK, Curran SR; CRESTAR Consortium. Spencer BW, et al. Among authors: maccabe jh. Pharmacogenomics. 2013 Nov;14(15):1907-14. doi: 10.2217/pgs.13.182. Pharmacogenomics. 2013. PMID: 24236489 Review.
187 results