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522 results

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Page 1
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Pan F, Wingo TS, Zhao Z, Gao R, Makishima H, Qu G, Lin L, Yu M, Ortega JR, Wang J, Nazha A, Chen L, Yao B, Liu C, Chen S, Weeks O, Ni H, Phillips BL, Huang S, Wang J, He C, Li GM, Radivoyevitch T, Aifantis I, Maciejewski JP, Yang FC, Jin P, Xu M. Pan F, et al. Among authors: maciejewski jp. Nat Commun. 2017 Apr 25;8:15102. doi: 10.1038/ncomms15102. Nat Commun. 2017. PMID: 28440315 Free PMC article.
250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies.
Dunbar AJ, Gondek LP, O'Keefe CL, Makishima H, Rataul MS, Szpurka H, Sekeres MA, Wang XF, McDevitt MA, Maciejewski JP. Dunbar AJ, et al. Among authors: maciejewski jp. Cancer Res. 2008 Dec 15;68(24):10349-57. doi: 10.1158/0008-5472.CAN-08-2754. Cancer Res. 2008. PMID: 19074904 Free PMC article.
Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies.
Makishima H, Cazzolli H, Szpurka H, Dunbar A, Tiu R, Huh J, Muramatsu H, O'Keefe C, Hsi E, Paquette RL, Kojima S, List AF, Sekeres MA, McDevitt MA, Maciejewski JP. Makishima H, et al. Among authors: maciejewski jp. J Clin Oncol. 2009 Dec 20;27(36):6109-16. doi: 10.1200/JCO.2009.23.7503. Epub 2009 Nov 9. J Clin Oncol. 2009. PMID: 19901108 Free PMC article.
Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia.
Muramatsu H, Makishima H, Jankowska AM, Cazzolli H, O'Keefe C, Yoshida N, Xu Y, Nishio N, Hama A, Yagasaki H, Takahashi Y, Kato K, Manabe A, Kojima S, Maciejewski JP. Muramatsu H, et al. Among authors: maciejewski jp. Blood. 2010 Mar 11;115(10):1969-75. doi: 10.1182/blood-2009-06-226340. Epub 2009 Dec 11. Blood. 2010. PMID: 20008299 Free PMC article.
Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutations.
Szpurka H, Jankowska AM, Makishima H, Bodo J, Bejanyan N, Hsi ED, Sekeres MA, Maciejewski JP. Szpurka H, et al. Among authors: maciejewski jp. Leuk Res. 2010 Aug;34(8):969-73. doi: 10.1016/j.leukres.2010.02.033. Epub 2010 Mar 23. Leuk Res. 2010. PMID: 20334914 Free PMC article.
Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations.
Sugimoto Y, Muramatsu H, Makishima H, Prince C, Jankowska AM, Yoshida N, Xu Y, Nishio N, Hama A, Yagasaki H, Takahashi Y, Kato K, Manabe A, Kojima S, Maciejewski JP. Sugimoto Y, et al. Among authors: maciejewski jp. Br J Haematol. 2010 Jul;150(1):83-7. doi: 10.1111/j.1365-2141.2010.08196.x. Epub 2010 Apr 12. Br J Haematol. 2010. PMID: 20408841 Free article.
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A. Ko M, et al. Among authors: maciejewski jp. Nature. 2010 Dec 9;468(7325):839-43. doi: 10.1038/nature09586. Nature. 2010. PMID: 21057493 Free PMC article.
522 results