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The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.
Andersen MK, Jørsboe E, Skotte L, Hanghøj K, Sandholt CH, Moltke I, Grarup N, Kern T, Mahendran Y, Søborg B, Bjerregaard P, Larsen CVL, Dahl-Petersen IK, Tiwari HK, Feenstra B, Koch A, Wiener HW, Hopkins SE, Pedersen O, Melbye M, Boyer BB, Jørgensen ME, Albrechtsen A, Hansen T. Andersen MK, et al. Among authors: mahendran y. PLoS Genet. 2020 Jan 24;16(1):e1008544. doi: 10.1371/journal.pgen.1008544. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31978080 Free PMC article.
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN, Madhu SV, Marwaha RK, Basu A, Scaria V, McCarthy MI; DIAGRAM; INDICO; Venkatesan R, Mohan V, Tandon N, Bharadwaj D. Tabassum R, et al. Diabetes. 2013 Mar;62(3):977-86. doi: 10.2337/db12-0406. Epub 2012 Dec 3. Diabetes. 2013. PMID: 23209189 Free PMC article.
Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology.
Schnurr TM, Gjesing AP, Sandholt CH, Jonsson A, Mahendran Y, Have CT, Ekstrøm CT, Bjerregaard AL, Brage S, Witte DR, Jørgensen ME, Aadahl M, Thuesen BH, Linneberg A, Eiberg H, Pedersen O, Grarup N, Kilpeläinen TO, Hansen T. Schnurr TM, et al. Among authors: mahendran y. PLoS One. 2016 Nov 15;11(11):e0166738. doi: 10.1371/journal.pone.0166738. eCollection 2016. PLoS One. 2016. PMID: 27846319 Free PMC article.
Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children.
Schnurr TM, Viitasalo A, Eloranta AM, Damsgaard CT, Mahendran Y, Have CT, Väistö J, Hjorth MF, Christensen LB, Brage S, Atalay M, Lyytikäinen LP, Lindi V, Lakka T, Michaelsen KF, Kilpeläinen TO, Hansen T. Schnurr TM, et al. Among authors: mahendran y. Int J Obes (Lond). 2018 Jan;42(1):111-114. doi: 10.1038/ijo.2017.235. Epub 2017 Sep 26. Int J Obes (Lond). 2018. PMID: 28947836 Free PMC article.
Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids.
Wewer Albrechtsen NJ, Færch K, Jensen TM, Witte DR, Pedersen J, Mahendran Y, Jonsson AE, Galsgaard KD, Winther-Sørensen M, Torekov SS, Lauritzen T, Pedersen O, Knop FK, Hansen T, Jørgensen ME, Vistisen D, Holst JJ. Wewer Albrechtsen NJ, et al. Among authors: mahendran y. Diabetologia. 2018 Mar;61(3):671-680. doi: 10.1007/s00125-017-4535-5. Epub 2018 Jan 5. Diabetologia. 2018. PMID: 29305624
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.
Grarup N, Moltke I, Andersen MK, Dalby M, Vitting-Seerup K, Kern T, Mahendran Y, Jørsboe E, Larsen CVL, Dahl-Petersen IK, Gilly A, Suveges D, Dedoussis G, Zeggini E, Pedersen O, Andersson R, Bjerregaard P, Jørgensen ME, Albrechtsen A, Hansen T. Grarup N, et al. Among authors: mahendran y. Nat Genet. 2018 Feb;50(2):172-174. doi: 10.1038/s41588-017-0022-7. Epub 2018 Jan 8. Nat Genet. 2018. PMID: 29311636 Free PMC article.
Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses.
Engelbrechtsen L, Mahendran Y, Jonsson A, Gjesing AP, Weeke PE, Jørgensen ME, Færch K, Witte DR, Holst JJ, Jørgensen T, Grarup N, Pedersen O, Vestergaard H, Torekov S, Kanters JK, Hansen T. Engelbrechtsen L, et al. Among authors: mahendran y. BMC Genet. 2018 Mar 16;19(1):15. doi: 10.1186/s12863-018-0602-2. BMC Genet. 2018. PMID: 29548277 Free PMC article.
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