Malinauskas T - Search Results

1

Structural insights into proteoglycan-shaped Hedgehog signaling.

Whalen DM, Malinauskas T, Gilbert RJ, Siebold C. Whalen DM, et al. Among authors: malinauskas t. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16420-5. doi: 10.1073/pnas.1310097110. Epub 2013 Sep 23. Proc Natl Acad Sci U S A. 2013. PMID: 24062467 Free PMC article.

2

Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.

Malinauskas T, Aricescu AR, Lu W, Siebold C, Jones EY. Malinauskas T, et al. Nat Struct Mol Biol. 2011 Jul 10;18(8):886-93. doi: 10.1038/nsmb.2081. Nat Struct Mol Biol. 2011. PMID: 21743455 Free PMC article.

3

Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling.

Chen S, Bubeck D, MacDonald BT, Liang WX, Mao JH, Malinauskas T, Llorca O, Aricescu AR, Siebold C, He X, Jones EY. Chen S, et al. Among authors: malinauskas t. Dev Cell. 2011 Nov 15;21(5):848-61. doi: 10.1016/j.devcel.2011.09.007. Epub 2011 Oct 13. Dev Cell. 2011. PMID: 22000855 Free PMC article.

4

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.

Janssen BJ, Malinauskas T, Weir GA, Cader MZ, Siebold C, Jones EY. Janssen BJ, et al. Among authors: malinauskas t. Nat Struct Mol Biol. 2012 Dec;19(12):1293-9. doi: 10.1038/nsmb.2416. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104057 Free PMC article.

5

Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.

Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Nachtergaele S, et al. Among authors: malinauskas t. Elife. 2013 Oct 29;2:e01340. doi: 10.7554/eLife.01340. Elife. 2013. PMID: 24171105 Free PMC article.

6

Structural insights into the inhibition of Wnt signaling by cancer antigen 5T4/Wnt-activated inhibitory factor 1.

Zhao Y, Malinauskas T, Harlos K, Jones EY. Zhao Y, et al. Among authors: malinauskas t. Structure. 2014 Apr 8;22(4):612-20. doi: 10.1016/j.str.2014.01.009. Epub 2014 Feb 27. Structure. 2014. PMID: 24582434 Free PMC article.

7

Structural Basis for Plexin Activation and Regulation.

Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ, Jones EY. Kong Y, et al. Among authors: malinauskas t. Neuron. 2016 Aug 3;91(3):548-60. doi: 10.1016/j.neuron.2016.06.018. Epub 2016 Jul 7. Neuron. 2016. PMID: 27397516 Free PMC article.

8

A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin-biased signaling.

Gorvin CM, Babinsky VN, Malinauskas T, Nissen PH, Schou AJ, Hanyaloglu AC, Siebold C, Jones EY, Hannan FM, Thakker RV. Gorvin CM, et al. Among authors: malinauskas t. Sci Signal. 2018 Feb 20;11(518):eaan3714. doi: 10.1126/scisignal.aan3714. Sci Signal. 2018. PMID: 29463778 Free PMC article.

9

Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational change and cause signalling bias.

Gorvin CM, Frost M, Malinauskas T, Cranston T, Boon H, Siebold C, Jones EY, Hannan FM, Thakker RV. Gorvin CM, et al. Among authors: malinauskas t. Hum Mol Genet. 2018 Nov 1;27(21):3720-3733. doi: 10.1093/hmg/ddy263. Hum Mol Genet. 2018. PMID: 30052933 Free PMC article.

10

Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.

Rozbesky D, Robinson RA, Jain V, Renner M, Malinauskas T, Harlos K, Siebold C, Jones EY. Rozbesky D, et al. Among authors: malinauskas t. Nat Commun. 2019 Aug 15;10(1):3691. doi: 10.1038/s41467-019-11683-y. Nat Commun. 2019. PMID: 31417095 Free PMC article.

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