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Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.
Corboz MR, Li Z, Malinin V, Plaunt AJ, Konicek DM, Leifer FG, Chen KJ, Laurent CE, Yin H, Biernat MC, Salvail D, Zhuang J, Xu F, Curran A, Perkins WR, Chapman RW. Corboz MR, et al. Among authors: malinin v. J Pharmacol Exp Ther. 2017 Dec;363(3):348-357. doi: 10.1124/jpet.117.242099. Epub 2017 Sep 13. J Pharmacol Exp Ther. 2017. PMID: 28904003
(99m)Tc-labeled therapeutic inhaled amikacin loaded liposomes.
Lee JH, Cheng KT, Malinin V, Li Z, Yao Z, Lee SJ, Gould CM, Olivier KN, Chen C, Perkins WR, Paik CH. Lee JH, et al. Among authors: malinin v. J Liposome Res. 2013 Dec;23(4):336-42. doi: 10.3109/08982104.2013.819889. Epub 2013 Jul 24. J Liposome Res. 2013. PMID: 23879241 Free PMC article.
Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil.
Chapman RW, Li Z, Corboz MR, Gauani H, Plaunt AJ, Konicek DM, Leifer FG, Laurent CE, Yin H, Salvail D, Dziak C, Perkins WR, Malinin V. Chapman RW, et al. Among authors: malinin v. Pulm Pharmacol Ther. 2018 Apr;49:104-111. doi: 10.1016/j.pupt.2018.02.002. Epub 2018 Feb 5. Pulm Pharmacol Ther. 2018. PMID: 29421665 Free article.
An overview of the biology of a long-acting inhaled treprostinil prodrug.
Chapman RW, Corboz MR, Malinin VS, Plaunt AJ, Konicek DM, Li Z, Perkins WR. Chapman RW, et al. Among authors: malinin vs. Pulm Pharmacol Ther. 2020 Dec;65:102002. doi: 10.1016/j.pupt.2021.102002. Epub 2021 Feb 15. Pulm Pharmacol Ther. 2020. PMID: 33596473 Free article. Review.
83 results