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A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.
Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber JH, Barrett A, Min JL, Rayner NW, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U; MolPAGE Consortium; Donnelly P, Illig T, Adamski J, Suhre K, Allen M, Zondervan KT, Spector TD, Nicholson JK, Lindon JC, Baunsgaard D, Holmes E, McCarthy MI, Holmes CC. Nicholson G, et al. Among authors: malmodin d. PLoS Genet. 2011 Sep;7(9):e1002270. doi: 10.1371/journal.pgen.1002270. Epub 2011 Sep 8. PLoS Genet. 2011. PMID: 21931564 Free PMC article.
Human metabolic profiles are stably controlled by genetic and environmental variation.
Nicholson G, Rantalainen M, Maher AD, Li JV, Malmodin D, Ahmadi KR, Faber JH, Hallgrímsdóttir IB, Barrett A, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U, The Molpage Consortium, Silverman BW, Donnelly P, Nicholson JK, Allen M, Zondervan KT, Lindon JC, Spector TD, McCarthy MI, Holmes E, Baunsgaard D, Holmes CC. Nicholson G, et al. Among authors: malmodin d. Mol Syst Biol. 2011 Aug 30;7:525. doi: 10.1038/msb.2011.57. Mol Syst Biol. 2011. PMID: 21878913 Free PMC article.
Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes.
Maher AD, Crockford D, Toft H, Malmodin D, Faber JH, McCarthy MI, Barrett A, Allen M, Walker M, Holmes E, Lindon JC, Nicholson JK. Maher AD, et al. Among authors: malmodin d. Anal Chem. 2008 Oct 1;80(19):7354-62. doi: 10.1021/ac801053g. Epub 2008 Aug 30. Anal Chem. 2008. PMID: 18759460
Metabonomics in diabetes research.
Faber JH, Malmodin D, Toft H, Maher AD, Crockford D, Holmes E, Nicholson JK, Dumas ME, Baunsgaard D. Faber JH, et al. Among authors: malmodin d. J Diabetes Sci Technol. 2007 Jul;1(4):549-57. doi: 10.1177/193229680700100413. J Diabetes Sci Technol. 2007. PMID: 19885118 Free PMC article.
25 results