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Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer.
Shlien A, Raine K, Fuligni F, Arnold R, Nik-Zainal S, Dronov S, Mamanova L, Rosic A, Ju YS, Cooke SL, Ramakrishna M, Papaemmanuil E, Davies HR, Tarpey PS, Van Loo P, Wedge DC, Jones DR, Martin S, Marshall J, Anderson E, Hardy C; ICGC Breast Cancer Working Group, Oslo Breast Cancer Research Consortium; Barbashina V, Aparicio SA, Sauer T, Garred Ø, Vincent-Salomon A, Mariani O, Boyault S, Fatima A, Langerød A, Borg Å, Thomas G, Richardson AL, Børresen-Dale AL, Polyak K, Stratton MR, Campbell PJ. Shlien A, et al. Among authors: mamanova l. Cell Rep. 2016 Aug 16;16(7):2032-46. doi: 10.1016/j.celrep.2016.07.028. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498871 Free PMC article.
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer.
Li R, Ferdinand JR, Loudon KW, Bowyer GS, Laidlaw S, Muyas F, Mamanova L, Neves JB, Bolt L, Fasouli ES, Lawson ARJ, Young MD, Hooks Y, Oliver TRW, Butler TM, Armitage JN, Aho T, Riddick ACP, Gnanapragasam V, Welsh SJ, Meyer KB, Warren AY, Tran MGB, Stewart GD, Cortés-Ciriano I, Behjati S, Clatworthy MR, Campbell PJ, Teichmann SA, Mitchell TJ. Li R, et al. Among authors: mamanova l. Cancer Cell. 2022 Dec 12;40(12):1583-1599.e10. doi: 10.1016/j.ccell.2022.11.001. Epub 2022 Nov 23. Cancer Cell. 2022. PMID: 36423636 Free PMC article.
Single cell derived mRNA signals across human kidney tumors.
Young MD, Mitchell TJ, Custers L, Margaritis T, Morales-Rodriguez F, Kwakwa K, Khabirova E, Kildisiute G, Oliver TRW, de Krijger RR, van den Heuvel-Eibrink MM, Comitani F, Piapi A, Bugallo-Blanco E, Thevanesan C, Burke C, Prigmore E, Ambridge K, Roberts K, Braga FAV, Coorens THH, Del Valle I, Wilbrey-Clark A, Mamanova L, Stewart GD, Gnanapragasam VJ, Rampling D, Sebire N, Coleman N, Hook L, Warren A, Haniffa M, Kool M, Pfister SM, Achermann JC, He X, Barker RA, Shlien A, Bayraktar OA, Teichmann SA, Holstege FC, Meyer KB, Drost J, Straathof K, Behjati S. Young MD, et al. Among authors: mamanova l. Nat Commun. 2021 Jun 23;12(1):3896. doi: 10.1038/s41467-021-23949-5. Nat Commun. 2021. PMID: 34162837 Free PMC article.
FRT-seq: amplification-free, strand-specific transcriptome sequencing.
Mamanova L, Andrews RM, James KD, Sheridan EM, Ellis PD, Langford CF, Ost TW, Collins JE, Turner DJ. Mamanova L, et al. Nat Methods. 2010 Feb;7(2):130-2. doi: 10.1038/nmeth.1417. Epub 2010 Jan 17. Nat Methods. 2010. PMID: 20081834 Free PMC article.
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.
Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S. Young MD, et al. Among authors: mamanova l. Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699. Science. 2018. PMID: 30093597 Free PMC article.
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Custers L, Khabirova E, Coorens THH, Oliver TRW, Calandrini C, Young MD, Vieira Braga FA, Ellis P, Mamanova L, Segers H, Maat A, Kool M, Hoving EW, van den Heuvel-Eibrink MM, Nicholson J, Straathof K, Hook L, de Krijger RR, Trayers C, Allinson K, Behjati S, Drost J. Custers L, et al. Among authors: mamanova l. Nat Commun. 2021 Mar 3;12(1):1407. doi: 10.1038/s41467-021-21675-6. Nat Commun. 2021. PMID: 33658498 Free PMC article.
A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates.
He P, Lim K, Sun D, Pett JP, Jeng Q, Polanski K, Dong Z, Bolt L, Richardson L, Mamanova L, Dabrowska M, Wilbrey-Clark A, Madissoon E, Tuong ZK, Dann E, Suo C, Goh I, Yoshida M, Nikolić MZ, Janes SM, He X, Barker RA, Teichmann SA, Marioni JC, Meyer KB, Rawlins EL. He P, et al. Among authors: mamanova l. Cell. 2022 Dec 8;185(25):4841-4860.e25. doi: 10.1016/j.cell.2022.11.005. Cell. 2022. PMID: 36493756 Free article.
MultiMAP: dimensionality reduction and integration of multimodal data.
Jain MS, Polanski K, Conde CD, Chen X, Park J, Mamanova L, Knights A, Botting RA, Stephenson E, Haniffa M, Lamacraft A, Efremova M, Teichmann SA. Jain MS, et al. Among authors: mamanova l. Genome Biol. 2021 Dec 20;22(1):346. doi: 10.1186/s13059-021-02565-y. Genome Biol. 2021. PMID: 34930412 Free PMC article.
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.
Kildisiute G, Kholosy WM, Young MD, Roberts K, Elmentaite R, van Hooff SR, Pacyna CN, Khabirova E, Piapi A, Thevanesan C, Bugallo-Blanco E, Burke C, Mamanova L, Keller KM, Langenberg-Ververgaert KPS, Lijnzaad P, Margaritis T, Holstege FCP, Tas ML, Wijnen MHWA, van Noesel MM, Del Valle I, Barone G, van der Linden R, Duncan C, Anderson J, Achermann JC, Haniffa M, Teichmann SA, Rampling D, Sebire NJ, He X, de Krijger RR, Barker RA, Meyer KB, Bayraktar O, Straathof K, Molenaar JJ, Behjati S. Kildisiute G, et al. Among authors: mamanova l. Sci Adv. 2021 Feb 5;7(6):eabd3311. doi: 10.1126/sciadv.abd3311. Print 2021 Feb. Sci Adv. 2021. PMID: 33547074 Free PMC article.
40 results