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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyll… See abstract for full author list ➔ Evangelou E, et al. Among authors: mangino m. Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x. Epub 2018 Sep 17. Nat Genet. 2018. PMID: 30224653 Free PMC article.
Mapping of a major locus that determines telomere length in humans.
Vasa-Nicotera M, Brouilette S, Mangino M, Thompson JR, Braund P, Clemitson JR, Mason A, Bodycote CL, Raleigh SM, Louis E, Samani NJ. Vasa-Nicotera M, et al. Among authors: mangino m. Am J Hum Genet. 2005 Jan;76(1):147-51. doi: 10.1086/426734. Epub 2004 Nov 1. Am J Hum Genet. 2005. PMID: 15520935 Free PMC article.
Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia.
Nsengimana J, Samani NJ, Hall AS, Balmforth AJ, Mangino M, Yuldasheva N, Maqbool A, Braund P, Burton P, Bishop DT, Ball SG, Barrett JH; British Heart Foundation Family Heart Study Research Group. Nsengimana J, et al. Among authors: mangino m. Eur J Hum Genet. 2007 Mar;15(3):313-9. doi: 10.1038/sj.ejhg.5201752. Epub 2006 Dec 6. Eur J Hum Genet. 2007. PMID: 17149386
Genomewide association analysis of coronary artery disease.
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, König IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H; WTCCC and the Cardiogenics Consortium. Samani NJ, et al. Among authors: mangino m. N Engl J Med. 2007 Aug 2;357(5):443-53. doi: 10.1056/NEJMoa072366. Epub 2007 Jul 18. N Engl J Med. 2007. PMID: 17634449 Free PMC article.
Rheumatoid arthritis association at 6q23.
Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, Donn R, Symmons D, Hider S, Bruce IN; Wellcome Trust Case Control Consortium; Wilson AG, Marinou I, Morgan A, Emery P; YEAR Consortium; Carter A, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Strachan D, Worthington J. Thomson W, et al. Nat Genet. 2007 Dec;39(12):1431-3. doi: 10.1038/ng.2007.32. Epub 2007 Nov 4. Nat Genet. 2007. PMID: 17982455 Free PMC article.
515 results