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Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.
Martin SES, Tan ZW, Itkonen HM, Duveau DY, Paulo JA, Janetzko J, Boutz PL, Törk L, Moss FA, Thomas CJ, Gygi SP, Lazarus MB, Walker S. Martin SES, et al. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545. doi: 10.1021/jacs.8b07328. Epub 2018 Oct 4. J Am Chem Soc. 2018. PMID: 30285435 Free PMC article.
Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9.
Itkonen HM, Poulose N, Steele RE, Martin SES, Levine ZG, Duveau DY, Carelli R, Singh R, Urbanucci A, Loda M, Thomas CJ, Mills IG, Walker S. Itkonen HM, et al. Mol Cancer Res. 2020 Oct;18(10):1512-1521. doi: 10.1158/1541-7786.MCR-20-0339. Epub 2020 Jul 1. Mol Cancer Res. 2020. PMID: 32611550 Free PMC article.
393 results