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HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.
Ramos-Montoya A, Lamb AD, Russell R, Carroll T, Jurmeister S, Galeano-Dalmau N, Massie CE, Boren J, Bon H, Theodorou V, Vias M, Shaw GL, Sharma NL, Ross-Adams H, Scott HE, Vowler SL, Howat WJ, Warren AY, Wooster RF, Mills IG, Neal DE. Ramos-Montoya A, et al. Among authors: massie ce. EMBO Mol Med. 2014 May;6(5):651-61. doi: 10.1002/emmm.201303581. EMBO Mol Med. 2014. PMID: 24737870 Free PMC article.
The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.
Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, Laskey RA, Caldas C, Brenton JD. Ahmed AA, et al. Among authors: massie ce. Cancer Cell. 2007 Dec;12(6):514-27. doi: 10.1016/j.ccr.2007.11.014. Cancer Cell. 2007. PMID: 18068629 Free PMC article.
ChIPping away at gene regulation.
Massie CE, Mills IG. Massie CE, et al. EMBO Rep. 2008 Apr;9(4):337-43. doi: 10.1038/embor.2008.44. EMBO Rep. 2008. PMID: 18379585 Free PMC article. Review.
Pro-neural transcription factors as cancer markers.
Vias M, Massie CE, East P, Scott H, Warren A, Zhou Z, Nikitin AY, Neal DE, Mills IG. Vias M, et al. Among authors: massie ce. BMC Med Genomics. 2008 May 19;1:17. doi: 10.1186/1755-8794-1-17. BMC Med Genomics. 2008. PMID: 18489756 Free PMC article.
Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer.
Attard G, Clark J, Ambroisine L, Mills IG, Fisher G, Flohr P, Reid A, Edwards S, Kovacs G, Berney D, Foster C, Massie CE, Fletcher A, De Bono JS, Scardino P, Cuzick J, Cooper CS; Transatlantic Prostate Group. Attard G, et al. Among authors: massie ce. Br J Cancer. 2008 Jul 22;99(2):314-20. doi: 10.1038/sj.bjc.6604472. Epub 2008 Jul 1. Br J Cancer. 2008. PMID: 18594527 Free PMC article.
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.
Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L, Warren A, Scott H, Madhu B, Sharma N, Bon H, Zecchini V, Smith DM, Denicola GM, Mathews N, Osborne M, Hadfield J, Macarthur S, Adryan B, Lyons SK, Brindle KM, Griffiths J, Gleave ME, Rennie PS, Neal DE, Mills IG. Massie CE, et al. EMBO J. 2011 May 20;30(13):2719-33. doi: 10.1038/emboj.2011.158. EMBO J. 2011. PMID: 21602788 Free PMC article.
122 results