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Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.
PLoS One. 2013;8(2):e56763. doi: 10.1371/journal.pone.0056763. Epub 2013 Feb 21.
PLoS One. 2013.
PMID: 23437231
Free PMC article.
Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes.
McDuffie M, Maybee NA, Keller SR, Stevens BK, Garmey JC, Morris MA, Kropf E, Rival C, Ma K, Carter JD, Tersey SA, Nunemaker CS, Nadler JL.
McDuffie M, et al. Among authors: maybee na.
Diabetes. 2008 Jan;57(1):199-208. doi: 10.2337/db07-0830. Epub 2007 Oct 16.
Diabetes. 2008.
PMID: 17940120
Free PMC article.
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Is anti-inflammatory therapy for type 2 diabetes mellitus ready for routine clinical practice?
Maybee NA, Worrall BB, Nadler JL.
Maybee NA, et al.
Nat Clin Pract Endocrinol Metab. 2007 Dec;3(12):806-7. doi: 10.1038/ncpendmet0645. Epub 2007 Sep 18.
Nat Clin Pract Endocrinol Metab. 2007.
PMID: 17876346
Free PMC article.
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