McCarthy MI - Search Results

1

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.

Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber JH, Barrett A, Min JL, Rayner NW, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U; MolPAGE Consortium; Donnelly P, Illig T, Adamski J, Suhre K, Allen M, Zondervan KT, Spector TD, Nicholson JK, Lindon JC, Baunsgaard D, Holmes E, McCarthy MI, Holmes CC. Nicholson G, et al. Among authors: mccarthy mi. PLoS Genet. 2011 Sep;7(9):e1002270. doi: 10.1371/journal.pgen.1002270. Epub 2011 Sep 8. PLoS Genet. 2011. PMID: 21931564 Free PMC article.

2

Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.

Wiltshire S, Frayling TM, Hattersley AT, Hitman GA, Walker M, Levy JC, O'Rahilly S, Groves CJ, Menzel S, Cardon LR, McCarthy MI. Wiltshire S, et al. Among authors: mccarthy mi. Am J Hum Genet. 2002 Feb;70(2):543-6. doi: 10.1086/338760. Epub 2001 Dec 20. Am J Hum Genet. 2002. PMID: 11753821 Free PMC article.

3

Evaluating the results of genomewide linkage scans of complex traits by locus counting.

Wiltshire S, Cardon LR, McCarthy MI. Wiltshire S, et al. Among authors: mccarthy mi. Am J Hum Genet. 2002 Nov;71(5):1175-82. doi: 10.1086/342976. Epub 2002 Sep 25. Am J Hum Genet. 2002. PMID: 12355401 Free PMC article.

4

How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage.

Wiltshire S, Morris AP, McCarthy MI, Cardon LR. Wiltshire S, et al. Among authors: mccarthy mi. Genet Epidemiol. 2005 Jan;28(1):1-10. doi: 10.1002/gepi.20023. Genet Epidemiol. 2005. PMID: 15493062

5

An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets.

Zeggini E, Rayner W, Morris AP, Hattersley AT, Walker M, Hitman GA, Deloukas P, Cardon LR, McCarthy MI. Zeggini E, et al. Among authors: mccarthy mi. Nat Genet. 2005 Dec;37(12):1320-2. doi: 10.1038/ng1670. Epub 2005 Oct 30. Nat Genet. 2005. PMID: 16258542

6

Will the real disease gene please stand up?

Shephard N, John S, Cardon L, McCarthy MI, Zeggini E. Shephard N, et al. Among authors: mccarthy mi. BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S66. doi: 10.1186/1471-2156-6-S1-S66. BMC Genet. 2005. PMID: 16451679 Free PMC article.

7

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.

Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI. Groves CJ, et al. Among authors: mccarthy mi. Diabetes. 2006 Sep;55(9):2640-4. doi: 10.2337/db06-0355. Diabetes. 2006. PMID: 16936215

8

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.

Weedon MN, McCarthy MI, Hitman G, Walker M, Groves CJ, Zeggini E, Rayner NW, Shields B, Owen KR, Hattersley AT, Frayling TM. Weedon MN, et al. Among authors: mccarthy mi. PLoS Med. 2006 Oct;3(10):e374. doi: 10.1371/journal.pmed.0030374. PLoS Med. 2006. PMID: 17020404 Free PMC article.

9

PASSIM--an open source software system for managing information in biomedical studies.

Viksna J, Celms E, Opmanis M, Podnieks K, Rucevskis P, Zarins A, Barrett A, Neogi SG, Krestyaninova M, McCarthy MI, Brazma A, Sarkans U. Viksna J, et al. Among authors: mccarthy mi. BMC Bioinformatics. 2007 Feb 9;8:52. doi: 10.1186/1471-2105-8-52. BMC Bioinformatics. 2007. PMID: 17291344 Free PMC article.

10

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.

Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JR, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney AS; Wellcome Trust Case Control Consortium (WTCCC); McCarthy MI, Hattersley AT. Zeggini E, et al. Among authors: mccarthy mi. Science. 2007 Jun 1;316(5829):1336-41. doi: 10.1126/science.1142364. Epub 2007 Apr 26. Science. 2007. PMID: 17463249 Free PMC article.

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