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The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists.
Lin LS, Kopka IE, Mumford RA, Magriotis PA, Lanza T Jr, Durette PL, Kamenecka T, Young DN, de Laszlo SE, McCauley E, Riper GV, Kidambi U, Egger LA, Tong X, Lyons K, Vincent S, Stearns R, Colletti A, Teffera Y, Fenyk-Melody J, Schmidt JA, MacCoss M, Hagmann WK. Lin LS, et al. Among authors: mccauley e. Bioorg Med Chem Lett. 2002 Feb 25;12(4):611-4. doi: 10.1016/s0960-894x(01)00818-6. Bioorg Med Chem Lett. 2002. PMID: 11844683
Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrins.
Lin LS, Lanza T Jr, McCauley E, Van Riper G, Kidambi U, Cao J, Egger LA, Mumford RA, Schmidt JA, MacCoss M, Hagmann WK. Lin LS, et al. Among authors: mccauley e. Bioorg Med Chem Lett. 2002 Jan 21;12(2):133-6. doi: 10.1016/s0960-894x(01)00705-3. Bioorg Med Chem Lett. 2002. PMID: 11755338
N-aryl 2,6-dimethoxybiphenylalanine analogues as VLA-4 antagonists.
Doherty GA, Kamenecka T, McCauley E, Van Riper G, Mumford RA, Tong S, Hagmann WK. Doherty GA, et al. Among authors: mccauley e. Bioorg Med Chem Lett. 2002 Mar 11;12(5):729-31. doi: 10.1016/s0960-894x(02)00009-4. Bioorg Med Chem Lett. 2002. PMID: 11858990
Remission, Recovery, Relapse, and Recurrence Rates for Suicide Attempts and Nonsuicidal Self-Injury for Suicidal Youth Treated With Dialectical Behavior Therapy or Supportive Therapy.
Berk MS, Gallop R, Asarnow JR, Adrian MC, Hughes JL, McCauley E. Berk MS, et al. Among authors: mccauley e. J Am Acad Child Adolesc Psychiatry. 2024 Feb 5:S0890-8567(24)00059-5. doi: 10.1016/j.jaac.2024.01.012. Online ahead of print. J Am Acad Child Adolesc Psychiatry. 2024. PMID: 38325518
304 results