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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.
Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X; 23andMe Research Team; HUNT All-In Psychiatry; Choquet H, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunter DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Loukola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stančáková A, Stefansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold B… See abstract for full author list ➔ Liu M, et al. Among authors: mcguire d. Nat Genet. 2019 Feb;51(2):237-244. doi: 10.1038/s41588-018-0307-5. Epub 2019 Jan 14. Nat Genet. 2019. PMID: 30643251 Free PMC article.
Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes.
Jiang Y, Chen S, McGuire D, Chen F, Liu M, Iacono WG, Hewitt JK, Hokanson JE, Krauter K, Laakso M, Li KW, Lutz SM, McGue M, Pandit A, Zajac GJM, Boehnke M, Abecasis GR, Vrieze SI, Zhan X, Jiang B, Liu DJ. Jiang Y, et al. Among authors: mcguire d. PLoS Genet. 2018 Jul 17;14(7):e1007452. doi: 10.1371/journal.pgen.1007452. eCollection 2018 Jul. PLoS Genet. 2018. PMID: 30016313 Free PMC article.
Model-based assessment of replicability for genome-wide association meta-analysis.
McGuire D, Jiang Y, Liu M, Weissenkampen JD, Eckert S, Yang L, Chen F; GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN); Berg A, Vrieze S, Jiang B, Li Q, Liu DJ. McGuire D, et al. Nat Commun. 2021 Mar 30;12(1):1964. doi: 10.1038/s41467-021-21226-z. Nat Commun. 2021. PMID: 33785739 Free PMC article.
Integrating 3D genomic and epigenomic data to enhance target gene discovery and drug repurposing in transcriptome-wide association studies.
Khunsriraksakul C, McGuire D, Sauteraud R, Chen F, Yang L, Wang L, Hughey J, Eckert S, Dylan Weissenkampen J, Shenoy G, Marx O, Carrel L, Jiang B, Liu DJ. Khunsriraksakul C, et al. Among authors: mcguire d. Nat Commun. 2022 Jun 7;13(1):3258. doi: 10.1038/s41467-022-30956-7. Nat Commun. 2022. PMID: 35672318 Free PMC article.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
Evaluation of the use of albumin controls in Rh phenotyping.
White WD, Issitt CH, McGuire D. White WD, et al. Among authors: mcguire d. Transfusion. 1974 Jan-Feb;14(1):67-71. doi: 10.1111/j.1537-2995.1974.tb04488.x. Transfusion. 1974. PMID: 4204587 No abstract available.
Rhmod, a second kindred (Craig).
McGuire D, Rosenfield RE, Wong KY, Heller C, Rubinstein P, Allen FH Jr, Walker ME, Lewis M. McGuire D, et al. Vox Sang. 1976;30(6):430-40. doi: 10.1111/j.1423-0410.1976.tb02848.x. Vox Sang. 1976. PMID: 818811
Limb Outcomes With Ticagrelor Plus Aspirin in Patients With Diabetes Mellitus and Atherosclerosis.
Bonaca MP, Bhatt DL, Simon T, Fox KM, Mehta S, Harrington RA, Leiter LA, Capell WH, Held C, Himmelmann A, Ridderstråle W, Chen J, Lee JJ, Song Y, Andersson M, Prats J, Kosiborod M, McGuire DK, Steg PG. Bonaca MP, et al. Among authors: mcguire dk. J Am Coll Cardiol. 2024 Apr 30;83(17):1627-1636. doi: 10.1016/j.jacc.2024.03.377. J Am Coll Cardiol. 2024. PMID: 38658101 Clinical Trial.
Putting More Weight on Obesity Trials in Heart Failure.
Harrington J, Sattar N, Felker GM, Januzzi JL, Lam CSP, Pagidipati NJ, Pandey A, Van Spall HGC, McGuire DK. Harrington J, et al. Among authors: mcguire dk. Curr Heart Fail Rep. 2024 Apr 15. doi: 10.1007/s11897-024-00655-z. Online ahead of print. Curr Heart Fail Rep. 2024. PMID: 38619690 Review.
822 results