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Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.
Chobanian HR, Guo Y, Liu P, Chioda MD, Fung S, Lanza TJ, Chang L, Bakshi RK, Dellureficio JP, Hong Q, McLaughlin M, Belyk KM, Krska SW, Makarewicz AK, Martel EJ, Leone JF, Frey L, Karanam B, Madeira M, Alvaro R, Shuman J, Salituro G, Terebetski JL, Jochnowitz N, Mistry S, McGowan E, Hajdu R, Rosenbach M, Abbadie C, Alexander JP, Shiao LL, Sullivan KM, Nargund RP, Wyvratt MJ, Lin LS, DeVita RJ. Chobanian HR, et al. Among authors: mclaughlin m. ACS Med Chem Lett. 2014 Apr 10;5(6):717-21. doi: 10.1021/ml5001239. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944750 Free PMC article.
Synthesis of antifungal glucan synthase inhibitors from enfumafungin.
Zhong YL, Gauthier DR Jr, Shi YJ, McLaughlin M, Chung JY, Dagneau P, Marcune B, Krska SW, Ball RG, Reamer RA, Yasuda N. Zhong YL, et al. Among authors: mclaughlin m. J Org Chem. 2012 Apr 6;77(7):3297-310. doi: 10.1021/jo300046v. Epub 2012 Mar 28. J Org Chem. 2012. PMID: 22423625
Synthesis of α-hydroxyacetophenones.
McLaughlin M, Belyk KM, Qian G, Reamer RA, Chen CY. McLaughlin M, et al. J Org Chem. 2012 Jun 1;77(11):5144-8. doi: 10.1021/jo3005556. Epub 2012 May 22. J Org Chem. 2012. PMID: 22568765
Nine-Step Stereoselective Synthesis of Islatravir from Deoxyribose.
Nawrat CC, Whittaker AM, Huffman MA, McLaughlin M, Cohen RD, Andreani T, Ding B, Li H, Weisel M, Tschaen DM. Nawrat CC, et al. Among authors: mclaughlin m. Org Lett. 2020 Mar 20;22(6):2167-2172. doi: 10.1021/acs.orglett.0c00239. Epub 2020 Feb 28. Org Lett. 2020. PMID: 32108487
Synthesis of a naphthyridone p38 MAP kinase inhibitor.
Chung JY, Cvetovich RJ, McLaughlin M, Amato J, Tsay FR, Jensen M, Weissman S, Zewge D. Chung JY, et al. Among authors: mclaughlin m. J Org Chem. 2006 Oct 27;71(22):8602-9. doi: 10.1021/jo061618f. J Org Chem. 2006. PMID: 17064039
1,512 results