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Page 1
Genomewide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy.
Chua KC, Xiong C, Ho C, Mushiroda T, Jiang C, Mulkey F, Lai D, Schneider BP, Rashkin SR, Witte JS, Friedman PN, Ratain MJ, McLeod HL, Rugo HS, Shulman LN, Kubo M, Owzar K, Kroetz DL. Chua KC, et al. Among authors: mcleod hl. Clin Pharmacol Ther. 2020 Sep;108(3):625-634. doi: 10.1002/cpt.1958. Epub 2020 Aug 2. Clin Pharmacol Ther. 2020. PMID: 32562552 Free PMC article.
The pharmacogenetics research network: from SNP discovery to clinical drug response.
Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Among authors: mcleod hl. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.
Creating and evaluating genetic tests predictive of drug response.
Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM. Weiss ST, et al. Among authors: mcleod hl. Nat Rev Drug Discov. 2008 Jul;7(7):568-74. doi: 10.1038/nrd2520. Epub 2008 Jun 20. Nat Rev Drug Discov. 2008. PMID: 18587383 Free PMC article. Review.
Platinum neurotoxicity pharmacogenetics.
McWhinney SR, Goldberg RM, McLeod HL. McWhinney SR, et al. Among authors: mcleod hl. Mol Cancer Ther. 2009 Jan;8(1):10-6. doi: 10.1158/1535-7163.MCT-08-0840. Mol Cancer Ther. 2009. PMID: 19139108 Free PMC article. Review.
Vascular endothelial growth factor pathway.
Maitland ML, Lou XJ, Ramirez J, Desai AA, Berlin DS, McLeod HL, Weichselbaum RR, Ratain MJ, Altman RB, Klein TE. Maitland ML, et al. Among authors: mcleod hl. Pharmacogenet Genomics. 2010 May;20(5):346-9. doi: 10.1097/FPC.0b013e3283364ed7. Pharmacogenet Genomics. 2010. PMID: 20124951 Free PMC article. Review. No abstract available.
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Innocenti F, Owzar K, Cox NL, Evans P, Kubo M, Zembutsu H, Jiang C, Hollis D, Mushiroda T, Li L, Friedman P, Wang L, Glubb D, Hurwitz H, Giacomini KM, McLeod HL, Goldberg RM, Schilsky RL, Kindler HL, Nakamura Y, Ratain MJ. Innocenti F, et al. Among authors: mcleod hl. Clin Cancer Res. 2012 Jan 15;18(2):577-84. doi: 10.1158/1078-0432.CCR-11-1387. Epub 2011 Dec 5. Clin Cancer Res. 2012. PMID: 22142827 Free PMC article.
A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL. Baldwin RM, et al. Among authors: mcleod hl. Clin Cancer Res. 2012 Sep 15;18(18):5099-109. doi: 10.1158/1078-0432.CCR-12-1590. Epub 2012 Jul 27. Clin Cancer Res. 2012. PMID: 22843789 Free PMC article. Clinical Trial.
587 results