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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC; Alzheimer's Disease Neuroimaging Initiative; van Duijn CM, B… See abstract for full author list ➔ Hollingworth P, et al. Among authors: mead s. Nat Genet. 2011 May;43(5):429-35. doi: 10.1038/ng.803. Epub 2011 Apr 3. Nat Genet. 2011. PMID: 21460840 Free PMC article.
Mapping the progression of progranulin-associated frontotemporal lobar degeneration.
Rohrer JD, Warren JD, Barnes J, Mead S, Beck J, Pepple T, Boyes R, Omar R, Collinge J, Stevens JM, Warrington EK, Rossor MN, Fox NC. Rohrer JD, et al. Among authors: mead s. Nat Clin Pract Neurol. 2008 Aug;4(8):455-60. doi: 10.1038/ncpneuro0869. Epub 2008 Jul 22. Nat Clin Pract Neurol. 2008. PMID: 18648346 Free PMC article.
Age of onset and death in inherited prion disease are heritable.
Webb TE, Whittaker J, Collinge J, Mead S. Webb TE, et al. Among authors: mead s. Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5;150B(4):496-501. doi: 10.1002/ajmg.b.30844. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 18729123
HECTD2 is associated with susceptibility to mouse and human prion disease.
Lloyd SE, Maytham EG, Pota H, Grizenkova J, Molou E, Uphill J, Hummerich H, Whitfield J, Alpers MP, Mead S, Collinge J. Lloyd SE, et al. Among authors: mead s. PLoS Genet. 2009 Feb;5(2):e1000383. doi: 10.1371/journal.pgen.1000383. Epub 2009 Feb 13. PLoS Genet. 2009. PMID: 19214206 Free PMC article.
453 results