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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology; Moebus S, Mecocci P,… See abstract for full author list ➔ Lambert JC, et al. Among authors: mecocci p. Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27. Nat Genet. 2013. PMID: 24162737 Free PMC article.
Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease.
Mariani E, Seripa D, Ingegni T, Nocentini G, Mangialasche F, Ercolani S, Cherubini A, Metastasio A, Pilotto A, Senin U, Mecocci P. Mariani E, et al. Among authors: mecocci p. J Neurol Sci. 2006 Sep 25;247(2):187-91. doi: 10.1016/j.jns.2006.05.043. Epub 2006 Jun 19. J Neurol Sci. 2006. PMID: 16784755
Insight, cognition and quality of life in Alzheimer's disease.
Hurt CS, Banerjee S, Tunnard C, Whitehead DL, Tsolaki M, Mecocci P, Kloszewska I, Soininen H, Vellas B, Lovestone S; AddNeuroMed Consortium. Hurt CS, et al. Among authors: mecocci p. J Neurol Neurosurg Psychiatry. 2010 Mar;81(3):331-6. doi: 10.1136/jnnp.2009.184598. Epub 2009 Oct 13. J Neurol Neurosurg Psychiatry. 2010. PMID: 19828481 Free article.
MRI measures of Alzheimer's disease and the AddNeuroMed study.
Simmons A, Westman E, Muehlboeck S, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Wahlund LO, Soininen H, Lovestone S, Evans A, Spenger C; AddNeuroMed Consortium. Simmons A, et al. Among authors: mecocci p. Ann N Y Acad Sci. 2009 Oct;1180:47-55. doi: 10.1111/j.1749-6632.2009.05063.x. Ann N Y Acad Sci. 2009. PMID: 19906260
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.
Thambisetty M, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Güntert A, Proitsi P, Powell J, Causevic M, Killick R, Lunnon K, Lynham S, Broadstock M, Choudhry F, Howlett DR, Williams RJ, Sharp SI, Mitchelmore C, Tunnard C, Leung R, Foy C, O'Brien D, Breen G, Furney SJ, Ward M, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Hodges A, Murphy DG, Parkins S, Richardson JC, Resnick SM, Ferrucci L, Wong DF, Zhou Y, Muehlboeck S, Evans A, Francis PT, Spenger C, Lovestone S. Thambisetty M, et al. Among authors: mecocci p. Arch Gen Psychiatry. 2010 Jul;67(7):739-48. doi: 10.1001/archgenpsychiatry.2010.78. Arch Gen Psychiatry. 2010. PMID: 20603455 Free PMC article.
APOE ε2 allele is associated with larger regional cortical thicknesses and volumes.
Liu Y, Paajanen T, Westman E, Zhang Y, Wahlund LO, Simmons A, Tunnard C, Sobow T, Proitsi P, Powell J, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, Lovestone S, Soininen H; AddNeuroMed Consortium. Liu Y, et al. Among authors: mecocci p. Dement Geriatr Cogn Disord. 2010;30(3):229-37. doi: 10.1159/000320136. Epub 2010 Sep 15. Dement Geriatr Cogn Disord. 2010. PMID: 20847553
396 results