Medina MW - Search Results

1

A large electronic-health-record-based genome-wide study of serum lipids.

Hoffmann TJ, Theusch E, Haldar T, Ranatunga DK, Jorgenson E, Medina MW, Kvale MN, Kwok PY, Schaefer C, Krauss RM, Iribarren C, Risch N. Hoffmann TJ, et al. Among authors: medina mw. Nat Genet. 2018 Mar;50(3):401-413. doi: 10.1038/s41588-018-0064-5. Epub 2018 Mar 5. Nat Genet. 2018. PMID: 29507422 Free PMC article.

2

A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts.

Veturi Y, Lucas A, Bradford Y, Hui D, Dudek S, Theusch E, Verma A, Miller JE, Kullo I, Hakonarson H, Sleiman P, Schaid D, Stein CM, Edwards DRV, Feng Q, Wei WQ, Medina MW, Krauss RM, Hoffmann TJ, Risch N, Voight BF, Rader DJ, Ritchie MD. Veturi Y, et al. Among authors: medina mw. Nat Genet. 2021 Jul;53(7):972-981. doi: 10.1038/s41588-021-00879-y. Epub 2021 Jun 17. Nat Genet. 2021. PMID: 34140684 Free PMC article.

3

Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort.

Oni-Orisan A, Hoffmann TJ, Ranatunga D, Medina MW, Jorgenson E, Schaefer C, Krauss RM, Iribarren C, Risch N. Oni-Orisan A, et al. Among authors: medina mw. Circ Genom Precis Med. 2018 Sep;11(9):e002043. doi: 10.1161/CIRCGEN.117.002043. Circ Genom Precis Med. 2018. PMID: 30354326 Free PMC article.

4

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort.

Haldar T, Oni-Orisan A, Hoffmann TJ, Schaefer C, Iribarren C, Krauss RM, Medina MW, Risch N. Haldar T, et al. Among authors: medina mw. Cardiovasc Diabetol. 2022 Jul 14;21(1):132. doi: 10.1186/s12933-022-01566-w. Cardiovasc Diabetol. 2022. PMID: 35836181 Free PMC article.

5

The role of HMGCR alternative splicing in statin efficacy.

Medina MW, Krauss RM. Medina MW, et al. Trends Cardiovasc Med. 2009 Jul;19(5):173-7. doi: 10.1016/j.tcm.2009.10.003. Trends Cardiovasc Med. 2009. PMID: 20005478 Free PMC article. Review.

6

RHOA is a modulator of the cholesterol-lowering effects of statin.

Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. Medina MW, et al. PLoS Genet. 2012;8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166513 Free PMC article.

7

Ancestry and other genetic associations with plasma PCSK9 response to simvastatin.

Theusch E, Medina MW, Rotter JI, Krauss RM. Theusch E, et al. Among authors: medina mw. Pharmacogenet Genomics. 2014 Oct;24(10):492-500. doi: 10.1097/FPC.0000000000000081. Pharmacogenet Genomics. 2014. PMID: 25089948 Free PMC article. Clinical Trial.

8

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change.

Oni-Orisan A, Haldar T, Ranatunga DK, Medina MW, Schaefer C, Krauss RM, Iribarren C, Risch N, Hoffmann TJ. Oni-Orisan A, et al. Among authors: medina mw. NPJ Genom Med. 2020 Jan 16;5:1. doi: 10.1038/s41525-019-0109-4. eCollection 2020. NPJ Genom Med. 2020. PMID: 31969989 Free PMC article.

9

[No title available]

[No authors listed] [No authors listed] PMID: 33446660

10

Effect of SLCO1B1 T521C on Statin-Related Myotoxicity With Use of Lovastatin and Atorvastatin.

Lu B, Sun L, Seraydarian M, Hoffmann TJ, Medina MW, Risch N, Iribarren C, Krauss RM, Oni-Orisan A. Lu B, et al. Among authors: medina mw. Clin Pharmacol Ther. 2021 Sep;110(3):733-740. doi: 10.1002/cpt.2337. Epub 2021 Jul 23. Clin Pharmacol Ther. 2021. PMID: 34114646 Free PMC article.

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