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Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.
Chiou J, Geusz RJ, Okino ML, Han JY, Miller M, Melton R, Beebe E, Benaglio P, Huang S, Korgaonkar K, Heller S, Kleger A, Preissl S, Gorkin DU, Sander M, Gaulton KJ. Chiou J, et al. Among authors: melton r. Nature. 2021 Jun;594(7863):398-402. doi: 10.1038/s41586-021-03552-w. Epub 2021 May 19. Nature. 2021. PMID: 34012112 Free PMC article.
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.
Zhu H, Wang G, Nguyen-Ngoc KV, Kim D, Miller M, Goss G, Kovsky J, Harrington AR, Saunders DC, Hopkirk AL, Melton R, Powers AC, Preissl S, Spagnoli FM, Gaulton KJ, Sander M. Zhu H, et al. Among authors: melton r. Dev Cell. 2023 May 8;58(9):727-743.e11. doi: 10.1016/j.devcel.2023.03.011. Epub 2023 Apr 10. Dev Cell. 2023. PMID: 37040771
CpG-creating mutations are costly in many human viruses.
Caudill VR, Qin S, Winstead R, Kaur J, Tisthammer K, Pineda EG, Solis C, Cobey S, Bedford T, Carja O, Eggo RM, Koelle K, Lythgoe K, Regoes R, Roy S, Allen N, Aviles M, Baker BA, Bauer W, Bermudez S, Carlson C, Castellanos E, Catalan FL, Chemel AK, Elliot J, Evans D, Fiutek N, Fryer E, Goodfellow SM, Hecht M, Hopp K, Hopson ED Jr, Jaberi A, Kinney C, Lao D, Le A, Lo J, Lopez AG, López A, Lorenzo FG, Luu GT, Mahoney AR, Melton RL, Nascimento GD, Pradhananga A, Rodrigues NS, Shieh A, Sims J, Singh R, Sulaeman H, Thu R, Tran K, Tran L, Winters EJ, Wong A, Pennings PS. Caudill VR, et al. Among authors: melton rl. Evol Ecol. 2020;34(3):339-359. doi: 10.1007/s10682-020-10039-z. Epub 2020 Apr 24. Evol Ecol. 2020. PMID: 32508375 Free PMC article.
An integrated map of cell type-specific gene expression in pancreatic islets.
Elgamal RM, Kudtarkar P, Melton RL, Mummey HM, Benaglio P, Okino ML, Gaulton KJ. Elgamal RM, et al. Among authors: melton rl. bioRxiv [Preprint]. 2023 Feb 4:2023.02.03.526994. doi: 10.1101/2023.02.03.526994. bioRxiv. 2023. PMID: 36778506 Free PMC article. Updated. Preprint.
160 results