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Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.
Boocock J, Leask M, Okada Y; Asian Genetic Epidemiology Network (AGEN) Consortium; Matsuo H, Kawamura Y, Shi Y, Li C, Mount DB, Mandal AK, Wang W, Cadzow M, Gosling AL, Major TJ, Horsfield JA, Choi HK, Fadason T, O'Sullivan J, Stahl EA, Merriman TR. Boocock J, et al. Among authors: merriman tr. Hum Mol Genet. 2020 Apr 15;29(6):923-943. doi: 10.1093/hmg/ddaa013. Hum Mol Genet. 2020. PMID: 31985003
Role of the urate transporter SLC2A9 gene in susceptibility to gout in New Zealand Māori, Pacific Island, and Caucasian case-control sample sets.
Hollis-Moffatt JE, Xu X, Dalbeth N, Merriman ME, Topless R, Waddell C, Gow PJ, Harrison AA, Highton J, Jones PB, Stamp LK, Merriman TR. Hollis-Moffatt JE, et al. Among authors: merriman tr, merriman me. Arthritis Rheum. 2009 Nov;60(11):3485-92. doi: 10.1002/art.24938. Arthritis Rheum. 2009. PMID: 19877038 Free article.
A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets.
Phipps-Green AJ, Hollis-Moffatt JE, Dalbeth N, Merriman ME, Topless R, Gow PJ, Harrison AA, Highton J, Jones PB, Stamp LK, Merriman TR. Phipps-Green AJ, et al. Among authors: merriman tr, merriman me. Hum Mol Genet. 2010 Dec 15;19(24):4813-9. doi: 10.1093/hmg/ddq412. Epub 2010 Sep 21. Hum Mol Genet. 2010. PMID: 20858603
The renal urate transporter SLC17A1 locus: confirmation of association with gout.
Hollis-Moffatt JE, Phipps-Green AJ, Chapman B, Jones GT, van Rij A, Gow PJ, Harrison AA, Highton J, Jones PB, Montgomery GW, Stamp LK, Dalbeth N, Merriman TR. Hollis-Moffatt JE, et al. Among authors: merriman tr. Arthritis Res Ther. 2012 Apr 27;14(2):R92. doi: 10.1186/ar3816. Arthritis Res Ther. 2012. PMID: 22541845 Free PMC article.
A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm.
Jones GT, Bown MJ, Gretarsdottir S, Romaine SP, Helgadottir A, Yu G, Tromp G, Norman PE, Jin C, Baas AF, Blankensteijn JD, Kullo IJ, Phillips LV, Williams MJ, Topless R, Merriman TR, Vasudevan TM, Lewis DR, Blair RD, Hill AA, Sayers RD, Powell JT, Deloukas P, Thorleifsson G, Matthiasson SE, Thorsteinsdottir U, Golledge J, Ariëns RA, Johnson A, Sohrabi S, Scott DJ, Carey DJ, Erdman R, Elmore JR, Kuivaniemi H, Samani NJ, Stefansson K, van Rij AM. Jones GT, et al. Among authors: merriman tr. Hum Mol Genet. 2013 Jul 15;22(14):2941-7. doi: 10.1093/hmg/ddt141. Epub 2013 Mar 27. Hum Mol Genet. 2013. PMID: 23535823 Free PMC article.
Population-specific effects of SLC17A1 genotype on serum urate concentrations and renal excretion of uric acid during a fructose load.
Dalbeth N, House ME, Gamble GD, Horne A, Purvis L, Stewart A, Merriman M, Cadzow M, Phipps-Green A, Merriman TR. Dalbeth N, et al. Among authors: merriman tr, merriman m. Ann Rheum Dis. 2014 Jan;73(1):313-4. doi: 10.1136/annrheumdis-2013-203767. Epub 2013 Jul 12. Ann Rheum Dis. 2014. PMID: 23852697 No abstract available.
325 results