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Page 1
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
Deming Y, Filipello F, Cignarella F, Cantoni C, Hsu S, Mikesell R, Li Z, Del-Aguila JL, Dube U, Farias FG, Bradley J, Budde J, Ibanez L, Fernandez MV, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleo A, Alcolea D, Clarimon J, Rami L, Molinuevo JL, Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Ewers M, Harari O, Haass C, Brett TJ, Benitez BA, Karch CM, Piccio L, Cruchaga C. Deming Y, et al. Among authors: mikesell r. Sci Transl Med. 2019 Aug 14;11(505):eaau2291. doi: 10.1126/scitranslmed.aau2291. Sci Transl Med. 2019. PMID: 31413141 Free PMC article.
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
Cignarella F, Filipello F, Bollman B, Cantoni C, Locca A, Mikesell R, Manis M, Ibrahim A, Deng L, Benitez BA, Cruchaga C, Licastro D, Mihindukulasuriya K, Harari O, Buckland M, Holtzman DM, Rosenthal A, Schwabe T, Tassi I, Piccio L. Cignarella F, et al. Among authors: mikesell r. Acta Neuropathol. 2020 Oct;140(4):513-534. doi: 10.1007/s00401-020-02193-z. Epub 2020 Aug 9. Acta Neuropathol. 2020. PMID: 32772264 Free PMC article.
TREM2 regulates microglial cell activation in response to demyelination in vivo.
Cantoni C, Bollman B, Licastro D, Xie M, Mikesell R, Schmidt R, Yuede CM, Galimberti D, Olivecrona G, Klein RS, Cross AH, Otero K, Piccio L. Cantoni C, et al. Among authors: mikesell r. Acta Neuropathol. 2015 Mar;129(3):429-47. doi: 10.1007/s00401-015-1388-1. Epub 2015 Jan 29. Acta Neuropathol. 2015. PMID: 25631124 Free PMC article.
African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants.
Schindler SE, Cruchaga C, Joseph A, McCue L, Farias FHG, Wilkins CH, Deming Y, Henson RL, Mikesell RJ, Piccio L, Llibre-Guerra JJ, Moulder KL, Fagan AM, Ances BM, Benzinger TLS, Xiong C, Holtzman DM, Morris JC. Schindler SE, et al. Among authors: mikesell rj. Neurol Genet. 2021 Mar 4;7(2):e571. doi: 10.1212/NXG.0000000000000571. eCollection 2021 Apr. Neurol Genet. 2021. PMID: 33884297 Free PMC article.
Predicting optimal response to B-cell depletion with rituximab in multiple sclerosis using CXCL13 index, magnetic resonance imaging and clinical measures.
Alvarez E, Piccio L, Mikesell RJ, Trinkaus K, Parks BJ, Naismith RT, Cross AH. Alvarez E, et al. Among authors: mikesell rj. Mult Scler J Exp Transl Clin. 2015 Dec 24;1:2055217315623800. doi: 10.1177/2055217315623800. eCollection 2015 Jan-Dec. Mult Scler J Exp Transl Clin. 2015. PMID: 28607711 Free PMC article.
Lack of adiponectin leads to increased lymphocyte activation and increased disease severity in a mouse model of multiple sclerosis.
Piccio L, Cantoni C, Henderson JG, Hawiger D, Ramsbottom M, Mikesell R, Ryu J, Hsieh CS, Cremasco V, Haynes W, Dong LQ, Chan L, Galimberti D, Cross AH. Piccio L, et al. Among authors: mikesell r. Eur J Immunol. 2013 Aug;43(8):2089-100. doi: 10.1002/eji.201242836. Epub 2013 Jun 7. Eur J Immunol. 2013. PMID: 23640763 Free PMC article.
Alterations of the gut mycobiome in patients with MS.
Shah S, Locca A, Dorsett Y, Cantoni C, Ghezzi L, Lin Q, Bokoliya S, Panier H, Suther C, Gormley M, Liu Y, Evans E, Mikesell R, Obert K, Salter A, Cross AH, Tarr PI, Lovett-Racke A, Piccio L, Zhou Y. Shah S, et al. Among authors: mikesell r. EBioMedicine. 2021 Sep;71:103557. doi: 10.1016/j.ebiom.2021.103557. Epub 2021 Aug 26. EBioMedicine. 2021. PMID: 34455391 Free PMC article.
Alterations of host-gut microbiome interactions in multiple sclerosis.
Cantoni C, Lin Q, Dorsett Y, Ghezzi L, Liu Z, Pan Y, Chen K, Han Y, Li Z, Xiao H, Gormley M, Liu Y, Bokoliya S, Panier H, Suther C, Evans E, Deng L, Locca A, Mikesell R, Obert K, Newland P, Wu Y, Salter A, Cross AH, Tarr PI, Lovett-Racke A, Piccio L, Zhou Y. Cantoni C, et al. Among authors: mikesell r. EBioMedicine. 2022 Feb;76:103798. doi: 10.1016/j.ebiom.2021.103798. Epub 2022 Jan 27. EBioMedicine. 2022. PMID: 35094961 Free PMC article.
20 results