Miller ML - Search Results

1

Design, synthesis, and biological evaluation of new-generation taxoids.

Ojima I, Chen J, Sun L, Borella CP, Wang T, Miller ML, Lin S, Geng X, Kuznetsova L, Qu C, Gallager D, Zhao X, Zanardi I, Xia S, Horwitz SB, Mallen-St Clair J, Guerriero JL, Bar-Sagi D, Veith JM, Pera P, Bernacki RJ. Ojima I, et al. Among authors: miller ml. J Med Chem. 2008 Jun 12;51(11):3203-21. doi: 10.1021/jm800086e. Epub 2008 May 9. J Med Chem. 2008. PMID: 18465846 Free PMC article.

2

Synthesis of novel C2-C3'N-linked macrocyclic taxoids by means of highly regioselective Heck macrocyclization.

Geng X, Miller ML, Lin S, Ojima I. Geng X, et al. Among authors: miller ml. Org Lett. 2003 Oct 2;5(20):3733-6. doi: 10.1021/ol0354627. Org Lett. 2003. PMID: 14507217

3

Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents.

Ojima I, Borella CP, Wu X, Bounaud PY, Oderda CF, Sturm M, Miller ML, Chakravarty S, Chen J, Huang Q, Pera P, Brooks TA, Baer MR, Bernacki RJ. Ojima I, et al. Among authors: miller ml. J Med Chem. 2005 Mar 24;48(6):2218-28. doi: 10.1021/jm049483y. J Med Chem. 2005. PMID: 15771464

4

Synthesis and structure-activity relationships of new second-generation taxoids.

Ojima I, Wang T, Miller ML, Lin S, Borella CP, Geng X, Pera P, Bernacki RJ. Ojima I, et al. Among authors: miller ml. Bioorg Med Chem Lett. 1999 Dec 20;9(24):3423-8. doi: 10.1016/s0960-894x(99)00629-0. Bioorg Med Chem Lett. 1999. PMID: 10617084

5

Chemistry and chemical biology of taxane anticancer agents.

Miller ML, Ojima I. Miller ML, et al. Chem Rec. 2001;1(3):195-211. doi: 10.1002/tcr.1008. Chem Rec. 2001. PMID: 11895119 Review.

6

Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies.

Miller ML, Roller EE, Wu X, Leece BA, Goldmacher VS, Chari RV, Ojima I. Miller ML, et al. Bioorg Med Chem Lett. 2004 Aug 2;14(15):4079-82. doi: 10.1016/j.bmcl.2004.05.027. Bioorg Med Chem Lett. 2004. PMID: 15225730

7

Synthesis and biological evaluation of novel taxoids designed for targeted delivery to tumors.

Baloglu E, Miller ML, Roller EE, Cavanagh EE, Leece BA, Goldmacher VS, Chari RV. Baloglu E, et al. Among authors: miller ml. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5885-8. doi: 10.1016/j.bmcl.2004.09.025. Bioorg Med Chem Lett. 2004. PMID: 15501062

8

Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.

Miller ML, Roller EE, Zhao RY, Leece BA, Ab O, Baloglu E, Goldmacher VS, Chari RV. Miller ML, et al. J Med Chem. 2004 Sep 23;47(20):4802-5. doi: 10.1021/jm049705s. J Med Chem. 2004. PMID: 15369381

9

Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs).

Reid EE, Archer KE, Shizuka M, McShea MA, Maloney EK, Ab O, Lanieri L, Wilhelm A, Ponte JF, Yoder NC, Chari RVJ, Miller ML. Reid EE, et al. Among authors: miller ml. Bioorg Med Chem Lett. 2019 Sep 1;29(17):2455-2458. doi: 10.1016/j.bmcl.2019.07.031. Epub 2019 Jul 19. Bioorg Med Chem Lett. 2019. PMID: 31350125

10

Disulfide-linked antibody-maytansinoid conjugates: optimization of in vivo activity by varying the steric hindrance at carbon atoms adjacent to the disulfide linkage.

Kellogg BA, Garrett L, Kovtun Y, Lai KC, Leece B, Miller M, Payne G, Steeves R, Whiteman KR, Widdison W, Xie H, Singh R, Chari RV, Lambert JM, Lutz RJ. Kellogg BA, et al. Bioconjug Chem. 2011 Apr 20;22(4):717-27. doi: 10.1021/bc100480a. Epub 2011 Mar 22. Bioconjug Chem. 2011. PMID: 21425776

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