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USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection.
Dagenais-Lussier X, Loucif H, Cadorel H, Blumberger J, Isnard S, Bego MG, Cohen ÉA, Routy JP, van Grevenynghe J; Montreal Primary Infection Study Group. Dagenais-Lussier X, et al. PLoS Pathog. 2019 Oct 28;15(10):e1008060. doi: 10.1371/journal.ppat.1008060. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31658294 Free PMC article.
HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness.
Jackson E, Zhang CX, Kiani Z, Lisovsky I, Tallon B, Del Corpo A, Gilbert L, Bruneau J, Thomas R, Côté P, Trottier B, LeBlanc R, Rouleau D, Tremblay C, Tsoukas CM, Routy JP, Ni X, Mabanga T, Bernard NF; Montreal Primary Infection Study Group. Jackson E, et al. PLoS One. 2017 Sep 22;12(9):e0185160. doi: 10.1371/journal.pone.0185160. eCollection 2017. PLoS One. 2017. PMID: 28938026 Free PMC article.