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Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis.
Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Gomez-Ospina N, et al. Among authors: moore dd. Nat Commun. 2016 Feb 18;7:10713. doi: 10.1038/ncomms10713. Nat Commun. 2016. PMID: 26888176 Free PMC article.
Bile acids activate YAP to promote liver carcinogenesis.
Anakk S, Bhosale M, Schmidt VA, Johnson RL, Finegold MJ, Moore DD. Anakk S, et al. Among authors: moore dd. Cell Rep. 2013 Nov 27;5(4):1060-9. doi: 10.1016/j.celrep.2013.10.030. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268772 Free PMC article.
Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis.
Kettner NM, Voicu H, Finegold MJ, Coarfa C, Sreekumar A, Putluri N, Katchy CA, Lee C, Moore DD, Fu L. Kettner NM, et al. Among authors: moore dd. Cancer Cell. 2016 Dec 12;30(6):909-924. doi: 10.1016/j.ccell.2016.10.007. Epub 2016 Nov 23. Cancer Cell. 2016. PMID: 27889186 Free PMC article.
320 results