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Page 1
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair.
Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA, Iser WB, Wollman BN, Morevati M, Li J, Kerr JS, Lu Q, Waltz TB, Tian J, Sinclair DA, Mattson MP, Nilsen H, Bohr VA. Fang EF, et al. Among authors: morevati m. Cell Metab. 2016 Oct 11;24(4):566-581. doi: 10.1016/j.cmet.2016.09.004. Cell Metab. 2016. PMID: 27732836 Free PMC article.
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway.
Fang EF, Waltz TB, Kassahun H, Lu Q, Kerr JS, Morevati M, Fivenson EM, Wollman BN, Marosi K, Wilson MA, Iser WB, Eckley DM, Zhang Y, Lehrmann E, Goldberg IG, Scheibye-Knudsen M, Mattson MP, Nilsen H, Bohr VA, Becker KG. Fang EF, et al. Among authors: morevati m. Sci Rep. 2017 Apr 11;7:46208. doi: 10.1038/srep46208. Sci Rep. 2017. PMID: 28397803 Free PMC article.
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA. Fang EF, et al. Among authors: morevati m. Nat Commun. 2019 Nov 21;10(1):5284. doi: 10.1038/s41467-019-13172-8. Nat Commun. 2019. PMID: 31754102 Free PMC article.
Sarcopenia, Aging and Prospective Interventional Strategies.
Waltz TB, Fivenson EM, Morevati M, Li C, Becker KG, Bohr VA, Fang EF. Waltz TB, et al. Among authors: morevati m. Curr Med Chem. 2018;25(40):5588-5596. doi: 10.2174/0929867324666170801095850. Curr Med Chem. 2018. PMID: 28762310 Free PMC article. Review.
Lamin A/C promotes DNA base excision repair.
Maynard S, Keijzers G, Akbari M, Ezra MB, Hall A, Morevati M, Scheibye-Knudsen M, Gonzalo S, Bartek J, Bohr VA. Maynard S, et al. Among authors: morevati m. Nucleic Acids Res. 2019 Dec 16;47(22):11709-11728. doi: 10.1093/nar/gkz912. Nucleic Acids Res. 2019. PMID: 31647095 Free PMC article.
Effect of NAD+ boosting on kidney ischemia-reperfusion injury.
Morevati M, Egstrand S, Nordholm A, Mace ML, Andersen CB, Salmani R, Olgaard K, Lewin E. Morevati M, et al. PLoS One. 2021 Jun 1;16(6):e0252554. doi: 10.1371/journal.pone.0252554. eCollection 2021. PLoS One. 2021. PMID: 34061900 Free PMC article.
Klotho and activin A in kidney injury: plasma Klotho is maintained in unilateral obstruction despite no upregulation of Klotho biosynthesis in the contralateral kidney.
Nordholm A, Mace ML, Gravesen E, Hofman-Bang J, Morevati M, Olgaard K, Lewin E. Nordholm A, et al. Among authors: morevati m. Am J Physiol Renal Physiol. 2018 May 1;314(5):F753-F762. doi: 10.1152/ajprenal.00528.2017. Epub 2017 Nov 29. Am J Physiol Renal Physiol. 2018. PMID: 29187373 Free PMC article.
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