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Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2.
Pepper C, Mahdi JG, Buggins AG, Hewamana S, Walsby E, Mahdi E, Al-Haza'a A, Mahdi AJ, Lin TT, Pearce L, Morgan L, Bowen ID, Brennan P, Fegan C. Pepper C, et al. Among authors: morgan l. Cell Prolif. 2011 Aug;44(4):380-90. doi: 10.1111/j.1365-2184.2011.00760.x. Epub 2011 Jun 6. Cell Prolif. 2011. PMID: 21645153 Free PMC article.
Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells.
Hamilton E, Pearce L, Morgan L, Robinson S, Ware V, Brennan P, Thomas NS, Yallop D, Devereux S, Fegan C, Buggins AG, Pepper C. Hamilton E, et al. Among authors: morgan l. Br J Haematol. 2012 Sep;158(5):589-99. doi: 10.1111/j.1365-2141.2012.09191.x. Epub 2012 Jun 19. Br J Haematol. 2012. PMID: 22712573 Free article.
SRC as a therapeutic target in breast cancer.
Morgan L, Nicholson RI, Hiscox S. Morgan L, et al. Endocr Metab Immune Disord Drug Targets. 2008 Dec;8(4):273-8. doi: 10.2174/187153008786848295. Endocr Metab Immune Disord Drug Targets. 2008. PMID: 19075780 Review.
1,443 results