Morgan RA - Search Results

1

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions.

Hughes MS, Yu YY, Dudley ME, Zheng Z, Robbins PF, Li Y, Wunderlich J, Hawley RG, Moayeri M, Rosenberg SA, Morgan RA. Hughes MS, et al. Among authors: morgan ra. Hum Gene Ther. 2005 Apr;16(4):457-72. doi: 10.1089/hum.2005.16.457. Hum Gene Ther. 2005. PMID: 15871677 Free PMC article.

2

Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.

Jones S, Peng PD, Yang S, Hsu C, Cohen CJ, Zhao Y, Abad J, Zheng Z, Rosenberg SA, Morgan RA. Jones S, et al. Among authors: morgan ra. Hum Gene Ther. 2009 Jun;20(6):630-40. doi: 10.1089/hum.2008.048. Hum Gene Ther. 2009. PMID: 19265475 Free PMC article.

3

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.

Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, Kammula US, Royal RE, Sherry RM, Wunderlich JR, Lee CC, Restifo NP, Schwarz SL, Cogdill AP, Bishop RJ, Kim H, Brewer CC, Rudy SF, VanWaes C, Davis JL, Mathur A, Ripley RT, Nathan DA, Laurencot CM, Rosenberg SA. Johnson LA, et al. Among authors: morgan ra. Blood. 2009 Jul 16;114(3):535-46. doi: 10.1182/blood-2009-03-211714. Epub 2009 May 18. Blood. 2009. PMID: 19451549 Free PMC article. Clinical Trial.

4

Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells.

Theoret MR, Cohen CJ, Nahvi AV, Ngo LT, Suri KB, Powell DJ Jr, Dudley ME, Morgan RA, Rosenberg SA. Theoret MR, et al. Among authors: morgan ra. Hum Gene Ther. 2008 Nov;19(11):1219-32. doi: 10.1089/hum.2008.083. Hum Gene Ther. 2008. PMID: 19848582 Free PMC article.

5

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.

Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Morgan RA, et al. Mol Ther. 2010 Apr;18(4):843-51. doi: 10.1038/mt.2010.24. Epub 2010 Feb 23. Mol Ther. 2010. PMID: 20179677 Free PMC article.

6

A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.

Yang S, Dudley ME, Rosenberg SA, Morgan RA. Yang S, et al. Among authors: morgan ra. J Immunother. 2010 Jul-Aug;33(6):648-58. doi: 10.1097/CJI.0b013e3181e311cb. J Immunother. 2010. PMID: 20551831 Free PMC article.

7

Adoptive cell therapy: genetic modification to redirect effector cell specificity.

Morgan RA, Dudley ME, Rosenberg SA. Morgan RA, et al. Cancer J. 2010 Jul-Aug;16(4):336-41. doi: 10.1097/PPO.0b013e3181eb3879. Cancer J. 2010. PMID: 20693844 Free PMC article. Review.

8

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, Davis JL, Morgan RA, Merino MJ, Sherry RM, Hughes MS, Kammula US, Phan GQ, Lim RM, Wank SA, Restifo NP, Robbins PF, Laurencot CM, Rosenberg SA. Parkhurst MR, et al. Among authors: morgan ra. Mol Ther. 2011 Mar;19(3):620-6. doi: 10.1038/mt.2010.272. Epub 2010 Dec 14. Mol Ther. 2011. PMID: 21157437 Free PMC article. Clinical Trial.

9

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.

Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, Rosenberg SA, Morgan RA. Zhang L, et al. Among authors: morgan ra. Mol Ther. 2011 Apr;19(4):751-9. doi: 10.1038/mt.2010.313. Epub 2011 Feb 1. Mol Ther. 2011. PMID: 21285960 Free PMC article.

10

Treating cancer with genetically engineered T cells.

Park TS, Rosenberg SA, Morgan RA. Park TS, et al. Among authors: morgan ra. Trends Biotechnol. 2011 Nov;29(11):550-7. doi: 10.1016/j.tibtech.2011.04.009. Epub 2011 Jun 12. Trends Biotechnol. 2011. PMID: 21663987 Free PMC article. Review.

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