Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria.
Brust TF, Morgenweck J, Kim SA, Rose JH, Locke JL, Schmid CL, Zhou L, Stahl EL, Cameron MD, Scarry SM, Aubé J, Jones SR, Martin TJ, Bohn LM.
Brust TF, et al. Among authors: morgenweck j.
Sci Signal. 2016 Nov 29;9(456):ra117. doi: 10.1126/scisignal.aai8441.
Sci Signal. 2016.
PMID: 27899527
Free PMC article.