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Page 1
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.
Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P, Holm MS, Cazzola M, Malcovati L, Tauro S, Bowen D, Boultwood J, Pellagatti A, Pimanda JE, Unnikrishnan A, Vyas P, Göhring G, Schlegelberger B, Tobiasson M, Kvalheim G, Constantinescu SN, Nerlov C, Nilsson L, Campbell PJ, Sandberg R, Papaemmanuil E, Hellström-Lindberg E, Linnarsson S, Jacobsen SE. Woll PS, et al. Cancer Cell. 2014 Jun 16;25(6):794-808. doi: 10.1016/j.ccr.2014.03.036. Epub 2014 May 15. Cancer Cell. 2014. PMID: 24835589 Free article.
The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts.
Nikpour M, Scharenberg C, Liu A, Conte S, Karimi M, Mortera-Blanco T, Giai V, Fernandez-Mercado M, Papaemmanuil E, Högstrand K, Jansson M, Vedin I, Wainscoat JS, Campbell P, Cazzola M, Boultwood J, Grandien A, Hellström-Lindberg E. Nikpour M, et al. Leukemia. 2013 Apr;27(4):889-896. doi: 10.1038/leu.2012.298. Epub 2012 Oct 16. Leukemia. 2013. PMID: 23070040 Free PMC article.
Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts.
Conte S, Katayama S, Vesterlund L, Karimi M, Dimitriou M, Jansson M, Mortera-Blanco T, Unneberg P, Papaemmanuil E, Sander B, Skoog T, Campbell P, Walfridsson J, Kere J, Hellström-Lindberg E. Conte S, et al. Br J Haematol. 2015 Nov;171(4):478-90. doi: 10.1111/bjh.13610. Epub 2015 Aug 10. Br J Haematol. 2015. PMID: 26255870 Free PMC article.
Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality.
Dimitriou M, Woll PS, Mortera-Blanco T, Karimi M, Wedge DC, Doolittle H, Douagi I, Papaemmanuil E, Jacobsen SE, Hellström-Lindberg E. Dimitriou M, et al. Among authors: mortera blanco t. Oncotarget. 2016 Nov 8;7(45):72685-72698. doi: 10.18632/oncotarget.12234. Oncotarget. 2016. PMID: 27683035 Free PMC article.
SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells.
Mortera-Blanco T, Dimitriou M, Woll PS, Karimi M, Elvarsdottir E, Conte S, Tobiasson M, Jansson M, Douagi I, Moarii M, Saft L, Papaemmanuil E, Jacobsen SEW, Hellström-Lindberg E. Mortera-Blanco T, et al. Blood. 2017 Aug 17;130(7):881-890. doi: 10.1182/blood-2017-03-776070. Epub 2017 Jun 20. Blood. 2017. PMID: 28634182 Free PMC article.
A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes.
Elvarsdóttir EM, Mortera-Blanco T, Dimitriou M, Bouderlique T, Jansson M, Hofman IJF, Conte S, Karimi M, Sander B, Douagi I, Woll PS, Hellström-Lindberg E. Elvarsdóttir EM, et al. Among authors: mortera blanco t. Leukemia. 2020 Jan;34(1):271-282. doi: 10.1038/s41375-019-0532-7. Epub 2019 Aug 2. Leukemia. 2020. PMID: 31375745 Free PMC article.
Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs.
Asimomitis G, Deslauriers AG, Kotini AG, Bernard E, Esposito D, Olszewska M, Spyrou N, Arango Ossa J, Mortera-Blanco T, Koche R, Nannya Y, Malcovati L, Ogawa S, Cazzola M, Aaronson SA, Hellström-Lindberg E, Papaemmanuil E, Papapetrou EP. Asimomitis G, et al. Among authors: mortera blanco t. Blood Adv. 2022 May 24;6(10):2992-3005. doi: 10.1182/bloodadvances.2021006325. Blood Adv. 2022. PMID: 35042235 Free PMC article.
Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome.
Guzzi N, Muthukumar S, Cieśla M, Todisco G, Ngoc PCT, Madej M, Munita R, Fazio S, Ekström S, Mortera-Blanco T, Jansson M, Nannya Y, Cazzola M, Ogawa S, Malcovati L, Hellström-Lindberg E, Dimitriou M, Bellodi C. Guzzi N, et al. Among authors: mortera blanco t. Nat Cell Biol. 2022 Mar;24(3):299-306. doi: 10.1038/s41556-022-00852-9. Epub 2022 Mar 15. Nat Cell Biol. 2022. PMID: 35292784 Free PMC article.
The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS.
Hofman IJF, Mortera-Blanco T, Moura PL, Vestlund J, Larsson SV, Elvarsdottir EM, Walldin G, Tobiasson M, Sander B, Dimitriou M, Jacobsen SW, Woll PS, Jädersten M, Hellström-Lindberg E. Hofman IJF, et al. Among authors: mortera blanco t. Blood Adv. 2022 Aug 23;6(16):4705-4709. doi: 10.1182/bloodadvances.2022007858. Blood Adv. 2022. PMID: 35728121 Free PMC article. No abstract available.
Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts.
Todisco G, Creignou M, Bernard E, Björklund AC, Moura PL, Tesi B, Mortera-Blanco T, Sander B, Jansson M, Walldin G, Barbosa I, Reinsbach SE, Hofman IJ, Nilsson C, Yoshizato T, Dimitriou M, Chang D, Olafsdottir S, Venckute Larsson S, Tobiasson M, Malcovati L, Woll P, Jacobsen SEW, Papaemmanuil E, Hellström-Lindberg E. Todisco G, et al. Among authors: mortera blanco t. Clin Cancer Res. 2023 Oct 13;29(20):4256-4267. doi: 10.1158/1078-0432.CCR-23-0538. Clin Cancer Res. 2023. PMID: 37498312 Free PMC article.
16 results