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Page 1
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.
Cortes A, Pulit SL, Leo PJ, Pointon JJ, Robinson PC, Weisman MH, Ward M, Gensler LS, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Bradbury LA, Elewaut D, Burgos-Vargas R, Stebbings S, Appleton L, Farrah C, Lau J, Haroon N, Mulero J, Blanco FJ, Gonzalez-Gay MA, Lopez-Larrea C, Bowness P, Gaffney K, Gaston H, Gladman DD, Rahman P, Maksymowych WP, Crusius JB, van der Horst-Bruinsma IE, Valle-Oñate R, Romero-Sánchez C, Hansen IM, Pimentel-Santos FM, Inman RD, Martin J, Breban M, Wordsworth BP, Reveille JD, Evans DM, de Bakker PI, Brown MA. Cortes A, et al. Among authors: mulero j. Nat Commun. 2015 May 21;6:7146. doi: 10.1038/ncomms8146. Nat Commun. 2015. PMID: 25994336 Free PMC article.
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.
International Genetics of Ankylosing Spondylitis Consortium (IGAS); Cortes A, Hadler J, Pointon JP, Robinson PC, Karaderi T, Leo P, Cremin K, Pryce K, Harris J, Lee S, Joo KB, Shim SC, Weisman M, Ward M, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Jiang L, Liu Y, Wu X, Bradbury LA, Elewaut D, Burgos-Vargas R, Stebbings S, Appleton L, Farrah C, Lau J, Kenna TJ, Haroon N, Ferreira MA, Yang J, Mulero J, Fernandez-Sueiro JL, Gonzalez-Gay MA, Lopez-Larrea C, Deloukas P, Donnelly P; Australo-Anglo-American Spondyloarthritis Consortium (TASC); Groupe Française d'Etude Génétique des Spondylarthrites (GFEGS); Nord-Trøndelag Health Study (HUNT); Spondyloarthritis Research Consortium of Canada (SPARCC); Wellcome Trust Case Control Consortium 2 (WTCCC2); Bowness P, Gafney K, Gaston H, Gladman DD, Rahman P, Maksymowych WP, Xu H, Crusius JB, van der Horst-Bruinsma IE, Chou CT, Valle-Oñate R, Romero-Sánchez C, Hansen IM, Pimentel-Santos FM, Inman RD, Videm V, Martin J, Breban M, Reveille JD, Evans DM, Kim TH, Wordsworth BP, Brown MA. International Genetics of Ankylosing Spondylitis Consortium (IGAS), et al. Among authors: mulero j. Nat Genet. 2013 Jul;45(7):730-8. doi: 10.1038/ng.2667. Epub 2013 Jun 9. Nat Genet. 2013. PMID: 23749187 Free PMC article.
ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients.
Robinson PC, Costello ME, Leo P, Bradbury LA, Hollis K, Cortes A, Lee S, Joo KB, Shim SC, Weisman M, Ward M, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Jiang L, Liu Y, Wu X, Elewaut D, Burgos-Vargas R, Gensler LS, Stebbings S, Haroon N, Mulero J, Fernandez-Sueiro JL, Gonzalez-Gay MA, Lopez-Larrea C, Bowness P, Gafney K, Gaston JS, Gladman DD, Rahman P, Maksymowych WP, Xu H, van der Horst-Bruinsma IE, Chou CT, Valle-Oñate R, Romero-Sánchez MC, Hansen IM, Pimentel-Santos FM, Inman RD, Martin J, Breban M, Evans D, Reveille JD, Kim TH, Wordsworth BP, Brown MA. Robinson PC, et al. Among authors: mulero j. Ann Rheum Dis. 2015 Aug;74(8):1627-9. doi: 10.1136/annrheumdis-2015-207416. Epub 2015 Apr 27. Ann Rheum Dis. 2015. PMID: 25917849 Free PMC article. No abstract available.
A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis.
Díaz-Peña R, Aransay AM, Suárez-Álvarez B, Bruges-Armas J, Rodríguez-Ezpeleta N, Regueiro M, Pimentel-Santos FM, Mulero J, Sánchez A, Collantes E, Queiro R, Ballina J, Alves H, López-Larrea C. Díaz-Peña R, et al. Among authors: mulero j. Ann Rheum Dis. 2012 May;71(5):714-7. doi: 10.1136/annrheumdis-2011-200661. Epub 2012 Jan 31. Ann Rheum Dis. 2012. PMID: 22294640
Fine mapping of a major histocompatibility complex in ankylosing spondylitis: association of the HLA-DPA1 and HLA-DPB1 regions.
Díaz-Peña R, Aransay AM, Bruges-Armas J, López-Vázquez A, Rodríguez-Ezpeleta N, Mendibil I, Sánchez A, Torre-Alonso JC, Bettencourt BF, Mulero J, Collantes E, López-Larrea C. Díaz-Peña R, et al. Among authors: mulero j. Arthritis Rheum. 2011 Nov;63(11):3305-12. doi: 10.1002/art.30555. Arthritis Rheum. 2011. PMID: 21769851 Free article.
A Single Nucleotide Polymorphism in the Il17ra Promoter Is Associated with Functional Severity of Ankylosing Spondylitis.
Vidal-Castiñeira JR, López-Vázquez A, Diaz-Peña R, Diaz-Bulnes P, Martinez-Camblor P, Coto E, Coto-Segura P, Bruges-Armas J, Pinto JA, Blanco FJ, Sánchez A, Mulero J, Queiro R, Lopez-Larrea C. Vidal-Castiñeira JR, et al. Among authors: mulero j. PLoS One. 2016 Jul 14;11(7):e0158905. doi: 10.1371/journal.pone.0158905. eCollection 2016. PLoS One. 2016. PMID: 27415816 Free PMC article.
The Phenotype of Axial Spondyloarthritis: Is It Dependent on HLA-B27 Status?
Coates LC, Baraliakos X, Blanco FJ, Blanco-Morales EA, Braun J, Chandran V, Fernandez-Sueiro JL, FitzGerald O, Gallagher P, Gladman DD, Gubar E, Korotaeva T, Loginova E, Lubrano E, Mulero J, Pinto-Tasende J, Queiro R, Sanz Sanz J, Szentpetery A, Helliwell PS. Coates LC, et al. Among authors: mulero j. Arthritis Care Res (Hoboken). 2021 Jun;73(6):856-860. doi: 10.1002/acr.24174. Arthritis Care Res (Hoboken). 2021. PMID: 32100954 Free article.
ERAP1 polymorphisms and haplotypes are associated with ankylosing spondylitis susceptibility and functional severity in a Spanish population.
Szczypiorska M, Sánchez A, Bartolomé N, Arteta D, Sanz J, Brito E, Fernández P, Collantes E, Martínez A, Tejedor D, Artieda M, Mulero J. Szczypiorska M, et al. Among authors: mulero j. Rheumatology (Oxford). 2011 Nov;50(11):1969-75. doi: 10.1093/rheumatology/ker229. Epub 2011 Aug 24. Rheumatology (Oxford). 2011. PMID: 21865284
Comparison of the clinical expression of patients with ankylosing spondylitis from Europe and Latin America.
Benegas M, Muñoz-Gomariz E, Font P, Burgos-Vargas R, Chaves J, Palleiro D, Maldonado Cocco J, Gutiérrez M, Sáenz R, Steckmen I, Rillo O, Mulero J, Sampaio-Barros P, Barcelos A, Vander Cruyssen B, Vazquez-Mellado J, Collantes Estevez E; RESPONDIA group; ASPECT study group; REGISPONSER study group. Benegas M, et al. Among authors: mulero j. J Rheumatol. 2012 Dec;39(12):2315-20. doi: 10.3899/jrheum.110687. Epub 2012 Nov 12. J Rheumatol. 2012. PMID: 23149388
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