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Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290.
Huang Z, Myhr C, Bathgate RA, Ho BA, Bueno A, Hu X, Xiao J, Southall N, Barnaeva E, Agoulnik IU, Marugan JJ, Ferrer M, Agoulnik AI. Huang Z, et al. Among authors: myhr c. Front Endocrinol (Lausanne). 2015 Aug 17;6:128. doi: 10.3389/fendo.2015.00128. eCollection 2015. Front Endocrinol (Lausanne). 2015. PMID: 26347712 Free PMC article.
Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile.
Wilson KJ, Xiao J, Chen CZ, Huang Z, Agoulnik IU, Ferrer M, Southall N, Hu X, Zheng W, Xu X, Wang A, Myhr C, Barnaeva E, George ER, Agoulnik AI, Marugan JJ. Wilson KJ, et al. Among authors: myhr c. Eur J Med Chem. 2018 Aug 5;156:79-92. doi: 10.1016/j.ejmech.2018.06.008. Epub 2018 Jun 7. Eur J Med Chem. 2018. PMID: 30006176 Free PMC article.
Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.
Kaftanovskaya EM, Ng HH, Soula M, Rivas B, Myhr C, Ho BA, Cervantes BA, Shupe TD, Devarasetty M, Hu X, Xu X, Patnaik S, Wilson KJ, Barnaeva E, Ferrer M, Southall NT, Marugan JJ, Bishop CE, Agoulnik IU, Agoulnik AI. Kaftanovskaya EM, et al. Among authors: myhr c. FASEB J. 2019 Nov;33(11):12435-12446. doi: 10.1096/fj.201901046R. Epub 2019 Aug 16. FASEB J. 2019. PMID: 31419161 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35554639
Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.
Esteban-Lopez M, Wilson KJ, Myhr C, Kaftanovskaya EM, Henderson MJ, Southall NT, Xu X, Wang A, Hu X, Barnaeva E, Ye W, George ER, Sherrill JT, Ferrer M, Morello R, Agoulnik IU, Marugan JJ, Agoulnik AI. Esteban-Lopez M, et al. Among authors: myhr c. Commun Biol. 2022 Nov 4;5(1):1183. doi: 10.1038/s42003-022-04143-9. Commun Biol. 2022. PMID: 36333465 Free PMC article.
14 results