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A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis.
Durán-Sotuela A, Fernandez-Moreno M, Suárez-Ulloa V, Vázquez-García J, Relaño S, Hermida-Gómez T, Balboa-Barreiro V, Lourido-Salas L, Calamia V, Fernandez-Puente P, Ruiz-Romero C, Fernández-Tajes J, Vaamonde-García C, de Andrés MC, Oreiro N, Blanco FJ, Rego-Perez I. Durán-Sotuela A, et al. Ann Rheum Dis. 2023 Jul;82(7):974-984. doi: 10.1136/ard-2022-223570. Epub 2023 Apr 6. Ann Rheum Dis. 2023. PMID: 37024296 Free PMC article.
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