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STAT4 deficiency reduces the development of atherosclerosis in mice.
Taghavie-Moghadam PL, Gjurich BN, Jabeen R, Krishnamurthy P, Kaplan MH, Dobrian AD, Nadler JL, Galkina EV. Taghavie-Moghadam PL, et al. Among authors: nadler jl. Atherosclerosis. 2015 Nov;243(1):169-78. doi: 10.1016/j.atherosclerosis.2015.08.045. Epub 2015 Sep 4. Atherosclerosis. 2015. PMID: 26386214 Free PMC article.
STAT4 contributes to adipose tissue inflammation and atherosclerosis.
Dobrian AD, Hatcher MA, Brotman JJ, Galkina EV, Taghavie-Moghadam P, Pei H, Haynes BA, Nadler JL. Dobrian AD, et al. Among authors: nadler jl. J Endocrinol. 2015 Oct;227(1):13-24. doi: 10.1530/JOE-15-0098. Epub 2015 Aug 18. J Endocrinol. 2015. PMID: 26285907 Free PMC article.
Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1.
Galkina EV, Butcher M, Keller SR, Goff M, Bruce A, Pei H, Sarembock IJ, Sanders JM, Nagelin MH, Srinivasan S, Kulkarni RN, Hedrick CC, Lattanzio FA, Dobrian AD, Nadler JL, Ley K. Galkina EV, et al. Among authors: nadler jl. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):247-56. doi: 10.1161/ATVBAHA.111.240358. Epub 2011 Dec 22. Arterioscler Thromb Vasc Biol. 2012. PMID: 22199371 Free PMC article.
Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds.
Cunnion KM, Krishna NK, Pallera HK, Pineros-Fernandez A, Rivera MG, Hair PS, Lassiter BP, Huyck R, Clements MA, Hood AF, Rodeheaver GT, Cottler PS, Nadler JL, Dobrian AD. Cunnion KM, et al. Among authors: nadler jl. PLoS One. 2017 Jan 20;12(1):e0170500. doi: 10.1371/journal.pone.0170500. eCollection 2017. PLoS One. 2017. PMID: 28107529 Free PMC article.
STAT4 is expressed in neutrophils and promotes antimicrobial immunity.
Mehrpouya-Bahrami P, Moriarty AK, De Melo P, Keeter WC, Alakhras NS, Nelson AS, Hoover M, Barrios MS, Nadler JL, Serezani CH, Kaplan MH, Galkina EV. Mehrpouya-Bahrami P, et al. Among authors: nadler jl. JCI Insight. 2021 Jul 22;6(14):e141326. doi: 10.1172/jci.insight.141326. JCI Insight. 2021. PMID: 34138758 Free PMC article.
257 results