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Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma.
Clin Cancer Res. 2015 May 15;21(10):2278-88. doi: 10.1158/1078-0432.CCR-14-2085. Epub 2015 Feb 18.
Clin Cancer Res. 2015.
PMID: 25695689
Free PMC article.
Clinical Trial.
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1.
Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME, Wunderlich JR, Nahvi AV, Helman LJ, Mackall CL, Kammula US, Hughes MS, Restifo NP, Raffeld M, Lee CC, Levy CL, Li YF, El-Gamil M, Schwarz SL, Laurencot C, Rosenberg SA.
Robbins PF, et al. Among authors: nahvi av.
J Clin Oncol. 2011 Mar 1;29(7):917-24. doi: 10.1200/JCO.2010.32.2537. Epub 2011 Jan 31.
J Clin Oncol. 2011.
PMID: 21282551
Free PMC article.
Clinical Trial.
Item in Clipboard
Evaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application.
Zhang L, Feldman SA, Zheng Z, Chinnasamy N, Xu H, Nahvi AV, Dudley ME, Rosenberg SA, Morgan RA.
Zhang L, et al. Among authors: nahvi av.
J Immunother. 2012 Jun;35(5):430-9. doi: 10.1097/CJI.0b013e31825898e8.
J Immunother. 2012.
PMID: 22576348
Free PMC article.
Item in Clipboard
A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma.
Dudley ME, Wunderlich JR, Yang JC, Hwu P, Schwartzentruber DJ, Topalian SL, Sherry RM, Marincola FM, Leitman SF, Seipp CA, Rogers-Freezer L, Morton KE, Nahvi A, Mavroukakis SA, White DE, Rosenberg SA.
Dudley ME, et al.
J Immunother. 2002 May-Jun;25(3):243-51. doi: 10.1097/01.CJI.0000016820.36510.89.
J Immunother. 2002.
PMID: 12000866
Free PMC article.
Clinical Trial.
Item in Clipboard
Cancer regression in patients after transfer of genetically engineered lymphocytes.
Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, Royal RE, Topalian SL, Kammula US, Restifo NP, Zheng Z, Nahvi A, de Vries CR, Rogers-Freezer LJ, Mavroukakis SA, Rosenberg SA.
Morgan RA, et al.
Science. 2006 Oct 6;314(5796):126-9. doi: 10.1126/science.1129003. Epub 2006 Aug 31.
Science. 2006.
PMID: 16946036
Free PMC article.
Clinical Trial.
Item in Clipboard
Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells.
Theoret MR, Cohen CJ, Nahvi AV, Ngo LT, Suri KB, Powell DJ Jr, Dudley ME, Morgan RA, Rosenberg SA.
Theoret MR, et al. Among authors: nahvi av.
Hum Gene Ther. 2008 Nov;19(11):1219-32. doi: 10.1089/hum.2008.083.
Hum Gene Ther. 2008.
PMID: 19848582
Free PMC article.
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