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A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN; METABRIC Group; Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C. Vollan HK, et al. Among authors: ng ck. Mol Oncol. 2015 Jan;9(1):115-27. doi: 10.1016/j.molonc.2014.07.019. Epub 2014 Aug 8. Mol Oncol. 2015. PMID: 25169931 Free PMC article.
Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes.
McBride DJ, Etemadmoghadam D, Cooke SL, Alsop K, George J, Butler A, Cho J, Galappaththige D, Greenman C, Howarth KD, Lau KW, Ng CK, Raine K, Teague J, Wedge DC, Cancer Study Group AO, Caubit X, Stratton MR, Brenton JD, Campbell PJ, Futreal PA, Bowtell DD. McBride DJ, et al. Among authors: ng ck. J Pathol. 2012 Aug;227(4):446-55. doi: 10.1002/path.4042. Epub 2012 Jul 2. J Pathol. 2012. PMID: 22514011 Free PMC article.
Chromosomal instability determines taxane response.
Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J. Swanton C, et al. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8671-6. doi: 10.1073/pnas.0811835106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458043 Free PMC article.
548 results