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RORγt and RORα signature genes in human Th17 cells.
Castro G, Liu X, Ngo K, De Leon-Tabaldo A, Zhao S, Luna-Roman R, Yu J, Cao T, Kuhn R, Wilkinson P, Herman K, Nelen MI, Blevitt J, Xue X, Fourie A, Fung-Leung WP. Castro G, et al. Among authors: ngo k. PLoS One. 2017 Aug 1;12(8):e0181868. doi: 10.1371/journal.pone.0181868. eCollection 2017. PLoS One. 2017. PMID: 28763457 Free PMC article.
Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-life.
Edwards W, Fung-Leung WP, Huang C, Chi E, Wu N, Liu Y, Maher MP, Bonesteel R, Connor J, Fellows R, Garcia E, Lee J, Lu L, Ngo K, Scott B, Zhou H, Swanson RV, Wickenden AD. Edwards W, et al. Among authors: ngo k. J Biol Chem. 2014 Aug 15;289(33):22704-22714. doi: 10.1074/jbc.M114.568642. Epub 2014 Jun 17. J Biol Chem. 2014. PMID: 24939846 Free PMC article.
Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.
Soroosh P, Wu J, Xue X, Song J, Sutton SW, Sablad M, Yu J, Nelen MI, Liu X, Castro G, Luna R, Crawford S, Banie H, Dandridge RA, Deng X, Bittner A, Kuei C, Tootoonchi M, Rozenkrants N, Herman K, Gao J, Yang XV, Sachen K, Ngo K, Fung-Leung WP, Nguyen S, de Leon-Tabaldo A, Blevitt J, Zhang Y, Cummings MD, Rao T, Mani NS, Liu C, McKinnon M, Milla ME, Fourie AM, Sun S. Soroosh P, et al. Among authors: ngo k. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12163-8. doi: 10.1073/pnas.1322807111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092323 Free PMC article.
Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor.
Cai Y, Yu J, Ren P, He J, Wu Z, Xiao K, Jia H, Wang J, Sai Y, Dai G, Li X, Su W, Ngo K, Castro G, Acton PD, Fung-Leung WP, Edwards JP, Venable J, Rao TS. Cai Y, et al. Among authors: ngo k. Pharmacol Res Perspect. 2020 Jan 13;8(1):e00559. doi: 10.1002/prp2.559. eCollection 2020 Feb. Pharmacol Res Perspect. 2020. PMID: 31956418 Free PMC article.
364 results