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Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP.
Wigmore EM, Hafferty JD, Hall LS, Howard DM, Clarke TK, Fabbri C, Lewis CM, Uher R, Navrady LB, Adams MJ, Zeng Y, Campbell A, Gibson J, Thomson PA, Hayward C, Smith BH, Hocking LJ, Padmanabhan S, Deary IJ, Porteous DJ, Mors O, Mattheisen M, Nicodemus KK, McIntosh AM. Wigmore EM, et al. Among authors: nicodemus kk. Pharmacogenomics J. 2020 Apr;20(2):329-341. doi: 10.1038/s41397-019-0067-3. Epub 2019 Jan 31. Pharmacogenomics J. 2020. PMID: 30700811 Free PMC article.
Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).
Wigmore EM, Clarke TK, Howard DM, Adams MJ, Hall LS, Zeng Y, Gibson J, Davies G, Fernandez-Pujals AM, Thomson PA, Hayward C, Smith BH, Hocking LJ, Padmanabhan S, Deary IJ, Porteous DJ, Nicodemus KK, McIntosh AM. Wigmore EM, et al. Among authors: nicodemus kk. Transl Psychiatry. 2017 Aug 15;7(8):e1205. doi: 10.1038/tp.2017.148. Transl Psychiatry. 2017. PMID: 28809859 Free PMC article.
Pharmaco-epidemiology of antidepressant exposure in a UK cohort record-linkage study.
Hafferty JD, Wigmore EM, Howard DM, Adams MJ, Clarke TK, Campbell AI, MacIntyre DJ, Nicodemus KK, Lawrie SM, Porteous DJ, McIntosh AM. Hafferty JD, et al. Among authors: nicodemus kk. J Psychopharmacol. 2019 Apr;33(4):482-493. doi: 10.1177/0269881119827888. Epub 2019 Feb 27. J Psychopharmacol. 2019. PMID: 30808242
The role of neuroticism in self-harm and suicidal ideation: results from two UK population-based cohorts.
Hafferty JD, Navrady LB, Adams MJ, Howard DM, Campbell AI, Whalley HC, Lawrie SM, Nicodemus KK, Porteous DJ, Deary IJ, McIntosh AM. Hafferty JD, et al. Among authors: nicodemus kk. Soc Psychiatry Psychiatr Epidemiol. 2019 Dec;54(12):1505-1518. doi: 10.1007/s00127-019-01725-7. Epub 2019 May 23. Soc Psychiatry Psychiatr Epidemiol. 2019. PMID: 31123787 Free PMC article.
A major role for common genetic variation in anxiety disorders.
Purves KL, Coleman JRI, Meier SM, Rayner C, Davis KAS, Cheesman R, Bækvad-Hansen M, Børglum AD, Wan Cho S, Jürgen Deckert J, Gaspar HA, Bybjerg-Grauholm J, Hettema JM, Hotopf M, Hougaard D, Hübel C, Kan C, McIntosh AM, Mors O, Bo Mortensen P, Nordentoft M, Werge T, Nicodemus KK, Mattheisen M, Breen G, Eley TC. Purves KL, et al. Among authors: nicodemus kk. Mol Psychiatry. 2020 Dec;25(12):3292-3303. doi: 10.1038/s41380-019-0559-1. Epub 2019 Nov 20. Mol Psychiatry. 2020. PMID: 31748690 Free PMC article.
Using tree-based methods for detection of gene-gene interactions in the presence of a polygenic signal: simulation study with application to educational attainment in the Generation Scotland Cohort Study.
Meijsen JJ, Rammos A, Campbell A, Hayward C, Porteous DJ, Deary IJ, Marioni RE, Nicodemus KK. Meijsen JJ, et al. Among authors: nicodemus kk. Bioinformatics. 2019 Jan 15;35(2):181-188. doi: 10.1093/bioinformatics/bty462. Bioinformatics. 2019. PMID: 29931044 Free PMC article.
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium; St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, Müller-Myhsok B, Świątkowska B, Schulze TG, Nöthen MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O'Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Landén M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA; Major Depressive Disorder Working Grou… See abstract for full author list ➔ Blokland GAM, et al. Biol Psychiatry. 2022 Jan 1;91(1):102-117. doi: 10.1016/j.biopsych.2021.02.972. Epub 2021 Mar 23. Biol Psychiatry. 2022. PMID: 34099189 Free PMC article.
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.
Ni G, Zeng J, Revez JA, Wang Y, Zheng Z, Ge T, Restuadi R, Kiewa J, Nyholt DR, Coleman JRI, Smoller JW; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Yang J, Visscher PM, Wray NR. Ni G, et al. Biol Psychiatry. 2021 Nov 1;90(9):611-620. doi: 10.1016/j.biopsych.2021.04.018. Epub 2021 May 4. Biol Psychiatry. 2021. PMID: 34304866 Free PMC article.
89 results